International Business Machines Corporation

Francesca Ruggeri

Armin W Knoll

Christian Michael Schwemmer

Thilo Hermann Curt Stoeferle

Darius Urbonas

A microfluidic device includes: a microchannel defining a flow path; a Brownian motor structure comprising two or more sorting channels having distinct ratchet topographies, the Brownian motor structure in fluid communication with the microchannel; and a filter extending transversely to the microchannel, the filter configured to filter particles, subject to sizes thereof, in a liquid advancing along the flow path, whereby smaller particles of the liquid can pass downstream of the filter in the flow path, and larger particles of the liquid are directed to the Brownian motor structure to be sorted out according to sizes thereof via the sorting channels.

Up-concentration and size sorting of nanoparticles in microfluidic devices

A detection device can include a cavity structure forming a Fabry-Perot optical microcavity, an electrostatic trap, and a Brownian motor. The Fabry-Perot optical microcavity has two mirrors extending on each side of a reference plane in a spacer region between the two mirrors. The mirrors are configured to vertically confine radiation in the spacer region, e.g., with respect to a first direction perpendicular to the reference plane. The electrostatic trap is arranged in the spacer region. The trap includes a pit and the cavity structure is generally configured to confine radiation in the pit, laterally (e.g., with respect to a second direction parallel to the reference plane). The Brownian motor structure extends in the spacer region along said reference plane. This structure is adapted to laterally load particles in the pit of the electrostatic trap by moving such particles along the structure, in operation.

Growing community of inventors

Zurich, Switzerland

Francesca Ruggeri