Laboratorios Cusi, S.a.

Francesc X Gimenez Guasch

Jose Alberto Vallet Mas

Alberto Vallet Mas

A dispenser for pharmaceutical solutions which includes membranes which are placed in a dropper of the dispenser and are used to achieve the flow of essentially all the active product and the retention of essentially all the preservative during pharmacological treatment. The membrane is coupled between two cylinder units on parts of the dropper, which remain in a relatively movable position, owing to the existence of a certain play between the cylinder units; or the cylinder units may be in a relatively fixed position, owing to the lack of such play. The cylinder unit may also be in a fixed position but with a membrane treated adequately so as to have a small area or 'stain' that permits the flow of air.

Use of polymeric membranes in the dispensing of pharmaceutical solutions

A pharmaceutical product container houses two separate substances. The container includes a bottom container having a first substance. The bottom container has an edge disposed at an open mouth thereof. A top container has a second substance. The top container has a frangible bottom wall. The top container has a flap extending radially outwardly. The flap includes an annular rib. The annular rib has a device for retaining the edge of the bottom container. The top container has a neck portion extending axially remote from the bottom wall. The neck has a helical thread to receive the cap. The neck includes a plurality of radially extending toothed projections about its perimeter. A tubular sleeve is disposed within the top container. The tubular sleeve is axially moveable with respect to the top container. The tubular sleeve has a first end and a second end. The first end has a device for partially cutting the bottom wall of the top container upon rotation of the cap onto the neck to create axial movement of the tubular sleeve in a first direction. The second end terminates with a radially protruding wing and a truncated-cone shaped portion. The truncated-cone shaped portion has a device for functioning as a medicinal dropper. A seal is connected to the cap with a perforated connection. The seal includes a plurality of radially extending toothed projections about its perimeter which mate with the plurality of projections in the neck such that upon rotation of the cap off of the neck, the perforated connection breaks and the seal can be removed. The cap can then be rotated onto the neck to effect the cutting of the bottom wall.

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Francesc X Gimenez Guasch