Massachusetts Institute of Technology

Frances E Nargi

Mark Alexander Hollis

James Douglas Harper

Todd H Rider

Trina Rae Vian

Eric D Schwoebel

Martha Susan Petrovick

Richard Hart Mathews

Bernadette Johnson

Joseph John Lacirignola

Kristine E Hogan

Mark Hennessy

Shaun R Berry

Raymond S Uttaro

Rose M Joseph

Albert M Young

Timothy Stephens

Linda Marie Mendenhall

Ann Rundell

Allan Heff

Songeeta Palchaudhuri

Eric Schwoebel

Joseph Lacirignola

Trina Vian

Richard H Mathews

Trina R Vian

The invention described herein provides methods for the detection of soluble antigens. In particular, the methods provide for the detection of soluble proteins and chemicals. In addition, the invention provides methods of detecting a nucleic acid sequence in a sample. Also described is an emittor cell comprising an Fc receptor and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more antibodies. Also provided is an optoelectronic sensor device for detecting a target particle in a plurality of samples.

Optoelectronic detection system

The invention described herein provides methods for the detection of target particles, such as pathogens, soluble antigens, nucleic acids, toxins, chemicals, plant pathogens, blood borne pathogens, bacteria, viruses and the like. Also described is an emittor cell comprising a receptor, wherein the receptor can be an antibody or an Fc receptor, and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more receptors on the emittor cell. Also provided are optoelectronic sensor devices for detecting a target particle in a sample, including in a plurality of samples.

Pathogen detection biosensor

The invention relates to optoelectronic systems for detecting one or more target particles. The system includes a reaction chamber, a specimen collector, an optical detector, and a reservoir containing cells, each of the cells having receptors which are present on the surface of each cell and are specific for the target particle to be detected, where binding of the target particle to the receptors directly or indirectly activates a reporter molecule, thereby producing a measurable optical signal.

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Littleton, MA, United States of America

Frances E Nargi