University of Washington

Forrest M Kievit

Miqin Zhang

Richard Glen Ellenbogen

Patrick S Stayton

Omid Veiseh

Pierre D Mourad

Anthony Convertine

Donghoon Lee

Menko P Ypma

Peter A Chiarelli

Joshua Sang Hun Park

Julia Mengyun Xu

Chen Fang

John R Silber

Zachary Stephen

Matthew Chi-hang Leung

Stephen Florczyk

Methods and compositions for treating traumatic brain injury. The methods and compositions utilize a multi-functional oxygen reactive polymer (ORP) that includes repeating units that include a reactive oxygen species (ROS) scavenging group and a polyalkylene oxide group. For theranostic applications, the oxygen reactive polymer further includes a diagnostic group.

Oxygen reactive polymers for treatment of traumatic brain injury

Polyarginine-coated nanoparticle, and methods for making and using the nanoparticle. The nanoparticle can have a core that includes a material that imparts magnetic resonance imaging activity to the particle and, optionally, include one or more of an associated therapeutic agent, targeting agent, and diagnostic agent.

Polyarginine-coated magnetic nanovector and methods of use thereof

Nanoparticle having a crosslinked chitosan-polyethylene oxide oligomer copolymer coating to which O-benzylguanine is covalently coupled, compositions that include the nanoparticle, and methods for using the nanoparticle to treat brain cancers.

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Methods for culturing cancer cells in vitro using a three-dimensional scaffold, scaffolds that include the cultured cancer cells, and methods for using the cultured cancer cells and the scaffolds that include the cultured cancer cells in anticancer therapeutic drug development.

Chitosan-alginate scaffold cell culture system and related methods

Growing community of inventors

Seattle, WA, United States of America

Forrest M Kievit