Ximo Ag

Verbio Vereinigte Bioenergie Ag

Givaudan S.a.

Florian Toth

Levente Ondi

Georg Emil Frater

Krisztian Lorincz

Csaba Hegedus

Jeno Varga

Emmanuel Robe

Agota Bucsai

Andreas Goeke

Christophe Coperet

Martin Alan Lovchik

Victor Mougel

Paul Nicholas Davey

Margherita Puccino

Michael Buchmeiser

Roman Schowner

Christophe COPÉRET

The disclosure provides Group 6 complexes, which, in some embodiments, are useful for catalyzing olefin metathesis reactions. In some embodiments, the compounds are compounds of the following formula: wherein:

Compounds and the use thereof in metathesis reactions

The invention relates to a method of forming an olefin from a first olefin and a second olefin in a metathesis reaction, comprising step (i): 

Metathesis catalysts and reactions using the catalysts

The invention relates to immobilized metal alkylidene catalysts. The catalysts are useful in olefin metathesis. 

Immobilized metal alkylidene catalysts and use thereof in olefin metathesis

A method is provided of forming an olefin from a first olefin and a second olefin in a metathesis reaction, comprising reacting the first olefin with the second olefin in the presence of a compound that catalyzes the metathesis reaction such that the molar ratio of the compound to the first or the second olefin is from 1:500 or less, and the conversion of the first or the second olefin to the olefin is at least 30%.

A method of forming a macrocyclic musk compound comprising the steps of:&#x2014;

Process involving cross metathesis of olefins

The disclosure provides Group 6 complexes, which, in some embodiments, are useful for catalyzing olefin metathesis reactions. In some embodiments, the compounds are compounds of the following formula (I) wherein: M is a Group 6 metal atom; X is an oxygen atom, &#x2550;N&#x2014;R, &#x2550;N&#x2014;N(R)(R) or &#x2550;N&#x2014;O&#x2014;R, Rand Rindependently being various substituents, such as aryl or heteroaryl, each optionally substituted; n is 0 or 1; Ris a neutral ligand; Ris hydrogen or an organic substituent; Ris an aryl or heteroaryl group, each optionally substituted; Ris an anionic ligand; and Ris an anionic ligand, such as a pyrrolide, a pyrazolide, an imidazolide, an indolide, an azaindolide, or an indazolide, each optionally substituted. 

The invention relates to a method of forming an olefin from a first olefin and a second olefin in a metathesis reaction, comprising step (i): (i) reacting the first olefin with the second olefin in the presence of a compound that catalyzes said metathesis reaction such that the molar ratio of said compound to the first or the second olefin is from 1:500 or less, and the conversion of the first or the second olefin to said olefin is at least 50%, characterized in that as compound that catalyzes said metathesis reaction a compound of formula (A) is used: wherein M is Mo or W; Ris aryl, heteroaryl, alkyl, or heteroalkyl; optionally substituted; Rand Rcan be the same or different and are hydrogen, alkyl, alkenyl, heteroalkyl, heteroalkenyl, aryl, or heteroaryl; optionally substituted; Ris alkyl, alkoxy, heteroalkyl, aryl, heteroaryl, silylalkyl, silyloxy, optionally substituted; and Ris a residue R&#x2014;X&#x2014;, wherein X&#x2550;O and Ris aryl, optionally substituted; or X&#x2550;S and Ris aryl, optionally substituted; or X&#x2550;O and Ris (R, R, R)Si; wherein R, R, Rare alkyl or phenyl, optionally substituted; or X&#x2550;O and Ris (R, R, R)C, wherein R, R, Rare independently selected from phenyl, alkyl; optionally substituted; and to the catalysts used in the method. 

Growing community of inventors

Horw/Lucerne, Switzerland

Florian Toth