Reuter Chemische Apparatebau Kg

Bridge Pharma Inc.

Biolotus Biotechnology Ag

Reuter Chemischer Apparatebau Kg

Mitsubishi Gas Chemical Company, Inc.

Reuter Chemische Apparatebau E.k.

Lumavita Ag

Florian Stolz

Karl Reuter

Viktor Meier

Mark Kantor

Vasyl Andrushko

Tobias Wedel

Koji Hirose

Noriyuki Kato

Shinya Ikeda

Kentaro Ishihara

A K Gunnar Aberg

Mitsuteru Kondo

Munenori Shiratake

Kensuke Oshima

Milan Soukup

Dieter Krimmer

Cees Winninps

Jofzsef Balint

Eliso Gogritchiani

Shoko Suzuki

Shuya Nagayama

Victor Meier

Shoko Murata

The present invention relates to a process for the preparation of enantiomerically enriched 3-aminopiperidine, as in particular of its R-enantiomer (R)-3-aminopiperidine. The invention also relates to an enantiomerically enriched intermediate of said process and to specific acid-addition salts of 3-aminopiperidine (hereinafter also APIP) that are useful for obtaining a single enantiomer of APIP, and to crystalline (R)-3-aminopiperidine-dihydrochloride-monohydrate and crystalline (S)-3-aminopiperidine-dihydrochloride-monohydrate.

Process for the preparation of enantiomerically enriched 3-aminopiperidine

The present invention relates to triarylmethane compounds of the formula (I), which suitable as monomers for preparing thermoplastic resins having beneficial optical properties and which can be used for producing optical devices. R, Rare e.g. hydrogen; Y is an alkylene group having 2, 3 or 4 carbon atoms, Ar is selected from mono- or polycyclic aryl and mono- or polycyclic hetaryl; X, X, X, Xare CH, C&#x2014;Ror N, provided that in each ring at most two of X, X, X, Xare N; Ris e.g. halogen, CN or CH&#x2550;CH. The invention also relates to thermoplastic resins comprising a polymerized unit of the compound of formula (I).

Triarylmethane compounds

The present invention relates to a process for the preparation of enantiomerically enriched 3-aminopiperidine, as in particular of its R-enantiomer (R)-3-aminopiperidine. The invention also relates to an enantiomerically enriched intermediate of said process and to specific acid-addition salts of 3-aminopiperidine (hereinafter also APIP) that are useful for obtaining a single enantiomer of APIP, and to crystalline (R)-3-aminopiperidine-dihydrochloride-monohydrateand crystalline (S)-3-aminopiperidine-dihydrochloride-monohydrate.

The present invention relates to binaphthyl compounds of the formula (I), which are suitable as monomers for preparing polycarbonate resins having beneficial optical properties and which can be used for producing optical lenses: Formula (I) where X is C-C-alkandiyl or C-C-alkandiyl-C(O)&#x2014;, where C(O) is bound to the oxygen atom of the hydroxyl group and where C-C-alkandiyl or C-C-alkandiyl, respectively, are unsubstituted or carry a phenyl ring; R and R' are identical or different and selected from mono or polycyclic aryl having from 6 to 36 carbon atoms and mono- or polycyclic hetaryl having a total of 5 to 36 atoms, which are ring members, where 1, 2, 3 or 4 of these atoms are selected from nitrogen, sulfur and oxygen, while the remainder of these atoms are carbon atoms, where mono- or polycyclic aryl and mono- or polycyclic hetaryl are unsubstituted or carry 1 or 2 radicals R, which are selected from the group consisting of CN, CH, OCH, O-phenyl, O-naphthyl, S-phenyl, S-naphthyl, CI or F; and, if X is C-C-alkandiyl-C(O)&#x2014;, the esters thereof, in particular the C-C-alkylesters thereof. 

Binaphthyl compounds

The present invention relates to a process for the preparation of enantiomerically enriched 3-aminopiperidine, and in particular of its R-enantiomer (R)-3-aminopiperidine. The invention also relates to an enantiomerically enriched intermediate of said process and to specific acid-addition salts of 3-aminopiperidine (hereinafter also APIP) that are useful for obtaining a single enantiomer of APIP, and to crystalline (R)-3-aminopiperidine-dihydrochloride-monohydrate and crystalline (S)-3-aminopiperidine-di-hydrochloride-monohydrate.

Described is pentamycin in a purity exceeding 95%, certain polymorphs and solvates of pentamycin, processes for their manufacture, and a method for decreasing the rate of degradation of pentamycin.

Highly pure pentamycin

Described is pentamycin in a purity exceeding 95%, certain polymorphs and solvates of pentamycin, processes for their manufacture, and a method for decreasing the rate of degradation of pentamycin. 

The invention relates to a process for preparing chiral octenoic acid derivatives, which constitute important intermediates in the preparation of medicament active ingredients, and also to novel intermediates which are used in the process for preparing the octenoic acid derivatives mentioned.

Process for preparing octenoic acid derivatives

Process for preparing chiral octenoic acid derivatives

A method of promoting weight loss in animals or humans by administering thereto a therapeutically effective amount of a mixture of RR-ractopamine and SR-ractopamine is disclosed.

Use of RR/SR-ractopamine

A method of promoting or improving the feed efficiency and the muscle-to-fat ratio in animals by administering to the animals a therapeutically effective amount of a mixture of RR-ractopamine and SR-ractopamine is disclosed. Manufacturing methods for making RR/SR-ractopamine are presented.

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Denzlingen, Germany

Florian Stolz