Ypsomed Ag

Roche Diagnostics International Ag

Roche Diabetes Care, Inc.

Roche Diagnostics Gmbh

F. Hoffmann-La Roche Ag

Florian Kühni

Christoph Huwiler

Andreas Schneider

Ulrich Haueter

Jürg Hirschel

Simon Scheurer

Andreas Geipel

Amir Feriani

Martin Wyss

Rudolf Zihlmann

Axel Remde

David Teutsch

Heiner Kaufmann

Leos Urbanek

Jürg Steck

Markus Oberli

Marc Labudde

Reto Schaltegger

Ueli Haueter

Simon Schüpbach

Krista Kappeler

Dominik Reubi

Martin Brügger

Ludovic Zulliger

Simon Dähler

Jörg Dogwiler

Gérald Studer

Jörg Dogwiller

Michael Häberli

Monitoring an injection process executed by a variable dose injection device with feedback means for generating a number of feedback events proportionate to the dose to be determined is disclosed. A dialed or injected dose is determined by measuring a first signal of the process comprising a first signal peak related to a feedback event; detecting the first signal peak in the first signal; selecting an evaluation interval comprising the detected peak and adapted to an expected peak duration; deriving, from the first signal limited to the evaluation interval, a feature or characterizing parameter of the feedback event; identifying, from the derived feature, the feedback event as one of a dial up, dial down, or expel feedback event, and counting identified feedback events to determine the dialed or the ejected dose. The two-stage approach with serially executed peak detection and peak identification allows to optimize data storage and processing power.

Click event identification in delivery devices

The disclosure is concerned with privacy and integrity of personalized protected health information when transmitted to a cloud computing facility and subsequently distributed to a plurality of stakeholders. An electronic unit of a drug delivery device is configured to prepare payload data comprising data items according to an allocation scheme, and to encrypt, based on an encryption key, and transmit data including the payload data. The allocation scheme and the encryption key are defined for each of a plurality of data subscribers. Accordingly, personalized protected health information payload data is suitably protected with generator-to-subscriber or pass-through data security measures, and any intermediary node or data server in the communication network lacking a matching decryption key will not have access to unencrypted payload data.

Secure drug delivery data transmission

A medical monitoring system increases patient safety and confidence. The system has a disposable injection device with a container holder for holding a container such as a cartridge or a syringe with a liquid drug for subcutaneous injection. The system includes a passive machine-readable tag mounted to a device housing of the injection device and coding or storing drug information about the drug in the container. The system also includes an electronic module or supplemental device releasably attachable to the injection device. The electronic module comprises injection status sensing means for monitoring a status of an injection or for tracking progress of a medication event, as well as a tag reader different from the sensing means for reading drug information from the machine-readable tag. The system includes a drug status signaling or interfacing unit for signaling to a user a drug status based on, or derived from, the drug information.

Monitoring of disposable injection devices

Micro-fluidic chambers for use in a liquid medicament delivery system, include a bottom substrate and a top cover, the top cover being spaced from the bottom substrate so as to define a height of the chamber, wherein, one or more walls or fillings are positioned in the chamber, the walls or fillings defining a fluid channel there between such that the fluid channel extends from an inlet conduit to an inlet of the chamber to an outlet conduit connected to an outlet of the chamber, wherein, each of the walls or fillings has a height less than the height of the chamber so as to define a fluid gap between a top surface of each wall or filling and the top cover; and wherein, the dimensions of the walls or fillings and the chamber are such that the fluid gap will be filled with liquid by capillary forces via the fluid channel when liquid is introduced into the fluid chamber.

Micro-fluidic chambers for use in liquid medicament delivery systems

Micro-fluidic chambers for use in a liquid medicament delivery system, include a bottom substrate and a top cover, the top cover being spaced from the bottom substrate so as to define a height of the chamber, wherein, one or more walls or fillings are positioned in the chamber, the walls or fillings defining a fluid channel there between such that the fluid channel extends from an inlet of the chamber to an outlet of the chamber, wherein, each of the walls or fillings has a height less than the height of the chamber so as to define a fluid gap between a top surface of each wall or filling and the top cover; and wherein, the dimensions of the walls or fillings and the chamber are such that the fluid gap will be filled with liquid by capillary forces via the fluid channel when liquid is introduced into the fluid chamber.

A flexible container for storing a liquid medicament and a device for the automated release of the liquid medicament from the flexible container are disclosed. The flexible container includes a wall and an access opening. The wall of the flexible container comprises two sheets of flexible material sealed together such that a storage volume intended to contain the liquid medicament is defined. The access opening provides a fluid connection to a conduit system in fluid connection with the storage volume via a fluid channel arranged between the storage volume and the access opening, wherein the fluid channel is formed by a cavity arranged on at least one of the two sheets.

Flexible container with a preformed fluid channel and infusion pump device using such a container

Growing community of inventors

Bern, Switzerland

Florian Kühni