Roche Diagnostics International Ag

Roche Diabetes Care, Inc.

Tecmed Ag

F. Hoffmann-la Roche Ag

Florian Kuehni

Ulrich Haueter

Martin Wyss

David Teutsch

Simon Scheurer

Andreas Geipel

Rudolf Zihlmann

Joerg Dogwiler

Reto Schaltegger

Christoph Huwiler

Ursina Streit

Patrick Hostettler

Thomas Buri

Gerald Studer

Markus Oberli

Christophe Hofer

Gilles Prod'hom

Thomas Leuzinger

Seline Staub

Marc Labudde

Martin Bruegger

Andreas Koehli

Juerg Steck

A disposable module that can be coupled to a reusable module in order to form a pump for dispensing a medicament substance to a user in a metered manner in a coupled state, comprising a housing that encases the following components: a reservoir for receiving the substance to be dispensed; and at least one extensible cannula, which is fluidically connected to the reservoir either after being inserted or in a permanent manner. The disposable module may also comprise an electrical energy store, wherein the electrical energy necessary for the reusable module can be obtained both from the disposable module and also from a rechargeable battery in the reusable module, in order to ensure redundancy of the energy necessary for the reusable module.

Patch pump

An infusion pump device and method for filling a fluidic system of the infusion pump with liquid medicament prior to infusion operation is presented. A control unit causes the infusion pump to: (a) bring a pump to an initial state; (b) switch a valve to a first state connecting a secondary reservoir to a first conduit and a primary reservoir; (c) retrieve medicament from the primary reservoir; (d) switch the valve to a second state connecting the secondary reservoir to a second downstream conduit; (e) expel the secondary reservoir contents into the second downstream conduit; (f) switch the valve to the first state; (g) retrieve the primary reservoir medicament; (h) switch the valve to the second state; and (i) expel the secondary reservoir contents into the second downstream conduit by shifting a piston to the initial position.

Infusion pump and method for improved filling of a fluidic system

A dosing device for an infusion system comprises a dosing unit having a variable volume and at least one opening in fluid connection with the variable volume, through which opening the variable volume can be filled with a substance or the substance can be dispensed from the variable volume. The dosing device is operable in a first state for filling the substance from a supply conduit, in a second state for preventing filling and dispensing, or in a third state for dispensing through a dispensing conduit. No direct fluid connection exists between the supply conduit and the dispensing conduit at any time. Methods for dosing a substance with the dosing device.

Dosing device for an infusion system and method thereof

A dosing unit for an ambulatory infusion pump device is presented. The dosing unit comprises a cylinder pump with a cylinder and a piston arranged in the cylinder. The piston has a shaft with a first threaded segment interacting with a threaded portion of the cylinder and can be displaced along a longitudinal axis of the cylinder by rotating the piston in regard to the cylinder around the axis. Furthermore, the piston allows for the relative or absolute determination of the longitudinal and/or rotational displacement of the piston in regard to the cylinder. In one embodiment, the piston shaft comprises a second segment provided with optically detectable markings that allow the monitoring of the longitudinal and/or rotational displacement of the piston in regard to the cylinder.

Dosing unit for an infusion pump device

An infusion pump device comprising a primary liquid medicament reservoir, a pump with a secondary reservoir to retrieve medicament from the primary reservoir and to subsequently dose the medicament from the secondary reservoir in adjustable volumes (V) to a downstream conduit and a control unit to control the operation of the infusion pump device is presented. For metering the volumes (V), the control unit causes the infusion pump device to: (a) determine a maximum refill level (V) for the secondary reservoir, based on external parameters, wherein the maximum refill level does not exceed the maximum capacity of the secondary reservoir; (b) fill the secondary reservoir with medicament from the primary reservoir to the maximum refill level (V); (c) meter and convey the medicament volumes to the downstream conduit; (d) if the secondary reservoir becomes empty, refill the secondary reservoir as in step (b) and continue with step (c).

Infusion pump device and method for improved dosing

A device for filling a flexible container and a method thereof are disclosed. The device may include a pressurizing chamber and an evacuation chamber. A first displacement piston is sealingly and slideably arranged within the pressurizing chamber to define an inner volume within the pressurizing chamber that is fluidly connected to a pressurizing conduit. A second displacement piston is sealingly and slideably arranged within the evacuation chamber to define an inner volume within the evacuation chamber that is fluidly connected to an evacuation conduit. A reservoir adapter is fluidly connected to the pressurizing conduit and connects to a liquid reservoir. A container adapter is fluidly connected to the evacuation conduit and connects with a flexible container. A transfer conduit is fluidly connected to the reservoir adapter and the container adapter. A valve fluidly connects the container adapter to the evacuation conduit or the transfer conduit.

Devices and methods for filling a flexible liquid medicament container with liquid from a liquid medicament reservoir

A dosing unit for an ambulatory infusion device and a method of operation are disclosed. The dosing unit includes a stationary member, a movable member, and a plunger. The movable member and the stationary member, together, make a charging valve and a discharging valve. The plunger is located, at least in part, in a metering cavity of the movable member and the movable member is adapted to selectively couple and decouple a driving unit, such that, by operating the driving unit with the movable member being coupled with the driving unit, the movable member moves with the plunger to maintain a position of the plunger relative to the movable member along a displacement axis, and by operating the driving unit with the movable member being decoupled from the driving unit, the plunger is displaced while the position of the movable member is maintained.

Dosing unit, ambulatory infusion device comprising dosing unit and method for operating a dosing unit

A device, kit, and method for transferring a liquid medicament from a supply container to a flexible reservoir container are disclosed. The device may comprise a compartment unit and an adapter unit. The compartment unit may have a sealingly closable chamber, arranged for housing the flexible reservoir container and for being fluidly connected with a pump mechanism. The adapter unit may have at least one transfer passage for transferring liquid from a supply container connected to the adapter unit to the flexible reservoir container, and a separator arranged in the transfer passage for separating gas bubbles from a liquid streaming through the transfer passage. The separator may be fluidly connected to the chamber.

Device, kit, and method for filling a flexible reservoir container in a negative pressure chamber

An automatically operating injection device with an occlusion alarm unit and a method for determining an injection occlusion are disclosed. The method includes generating a plurality of evaluation forces based on a series of force measurements and based on an evaluation time period; determining whether an occlusion exists based on either an evaluation of the plurality of evaluation forces or whether one or more of the series of force measurements exceeds a force threshold; and providing an injection occlusion alarm if an occlusion is determined to exist.

Automatically operating injection device and method for determining an injection occlusion

Growing community of inventors

Wabern, Switzerland

Florian Kuehni