Lts Lohmann Therapie-systeme Ag

Florian Hammes

René Eifler

Michael Linn

Markus Müller

Tobias Kleudgen

Anja Tomeleri

Mario Ficker

Tobias Tellkamp-schehr

Julia Lodder-gadaczek

Michael Orth

The invention relates to systems formed from closed liquid-tight packaging and a preferably dimensionally stable aqueous composition which is sealed therein and which, upon activation, releases a liquid phase essentially composed of water in a time-delayed manner. The invention further relates to methods for manufacturing such systems and the use thereof during the production of self-decomposing transdermal therapeutic systems (TTS).

Controlling water release from a dimensionally stable aqueous composition

Described is an oral thin film comprising at least one matrix layer, wherein the at least one matrix layer comprises at least one pharmaceutically active agent, at least one polyvinyl alcohol and at least one polyvinyl alcohol-polyethylene glycol graft copolymer, a method for producing same, and use thereof as a medicament.

Oral thin film of polyvinyl alcohol and polyvinyl alcohol-polyethylene glycol graft copolymer

The present invention concerns a transdermal therapeutic system, comprising a backing layer, which is not permeable for the active ingredient, and a matrix layer on one side of the backing layer, wherein the matrix layer contains at least one pressure sensitive adhesive and ketamine or a pharmaceutically acceptable salt or solvate thereof, wherein the at least one pressure sensitive adhesive has free hydroxyl groups, as well as its use as medicament, in particular for the treatment of depression and pain.

Transdermal therapeutic system

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Andernach, Germany

Florian Hammes