Ucb Pharma, S.a.

Florence Lebon

Patrice Talaga

Regorius Leurs

Sylvain Celanire

Frederic Denonne

Henkdrik Timmerman

The present invention relates to compounds comprising an oxazoline or thiazoline moiety, processes for preparing them, pharmaceutical compositions comprising said compounds and their uses as H-receptor ligands, (I), wherein Ais CH C(CH) or N; Ris hydrogen or halogen; Ris (II); Ais O or S; Ris hydrogen, halogen, Calkyl or Calkoxy; Ris hydrogen, halogen, Calkyl, Calkoxy, trifluoromethyl or &#x2014;O&#x2014;(CH)n-NReach CHin &#x2014;O&#x2014;(CH)n-NR12b being optionally substituted by one or two Calkyl; Ris hydrogen or &#x2014;O&#x2014;(CH)&#x2014;NR, each CHin &#x2014;O&#x2014;(CH)&#x2014;NRRbeing optionally substituted by one or two Calkyl, and at least one of Rand Rshould be a &#x2014;O&#x2014;(CH)n-NRRgroup. 

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Lillois, Belgium

Florence Lebon