Adare Pharmaceuticals S.r.l.

Adare Pharmaceuticals, Inc.

Aptalis Pharma Limited

Laboratorio Chimico Internazionale S.p.a.

Flavio Fabiani

Luigi Boltri

Luigi Giovanni Mapelli

Paolo Gatti

Mauro Serratoni

Roberto Cassanmagnago

Gopi M Venkatesh

Jin-Wang Lai

Antonio Nardi

Annibale Salvi

Flavio Villani

Christian Stollberg

Paolo Magri'

Italo Colombo

Giancarla Bianchi

The present invention is directed to pharmaceutical compositions and dosage forms comprising TPR beads, wherein said TPR beads comprise a solid dispersion of at least one active pharmaceutical ingredient in at least one solubility-enhancing polymer, and a TPR coating comprising a water insoluble polymer and an enteric polymer, wherein the active pharmaceutical ingredient comprises a weakly basic active pharmaceutical ingredient having a solubility of not more than 100 &#x3bc;g/mL at pH 6.8.

Drug delivery systems comprising solid solutions of weakly basic drugs

The present invention provides a pharmaceutical composition comprising taste-masked immediate release microcapsules which comprise fexofenadine and a water-insoluble polymer coating. These microcapsules and the pharmaceutical compositions comprising them have suitable drug content and desirable pharmaceutical properties, including a quick dissolution rate of fexofenadine combined with a taste masking effect.

Fexofenadine microcapsules and compositions containing them

The present invention provides a microcapsule pharmaceutical composition of at least a bisquinoline drug. said microcapsule comprises a drug core of a pharmaceutically effective amount of a bisquinoline drug and a polymeric coating over the core. This microcapsule pharmaceutical composition has desirable pharmaceutical properties, including taste masking effect and a high stability.

Piperaquine microcapsules and compositions containing them

Lipoic acid pellets are described, obtained from inert cores externally coated with lipoic acid. The so obtained active cores are coated with a first layer of insulating polymeric material and then with a polymeric coat that is insoluble at the gastric pH. Pellet are then formulated pharmaceutically, for instance in jelly capsules or controlled release capsules or as oral suspensions, dispersible powders, sachets, etc.

Lipoic acid pellets

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Ronco Briantino, Italy

Flavio Fabiani