Molecular Devices Corporation

Bio-rad Laboratories, Inc.

Fiona Lucy Plows

Michael G Youngquist

Timothy Arthur Floto

Alison Amy Glaser

Steven Andrew Roth

Mariana Rusa

System, including methods and apparatus, for identifying and picking spectrally distinct colonies. In an exemplary method, a filter may be received in an optical path extending from a light source to a grayscale image detector. The filter may be configured to increase an intensity difference between a first type of colony and a spectrally distinct second type of colony. Colonies including both types may be received in the optical path. An image of the colonies may be obtained with the grayscale image detector. At least one of the types of colony may be identified in the image. One or more colonies of the at least one type may be picked robotically.

System for identifying and picking spectrally distinct colonies

The present invention provides methods for using detection methods, including mass spectrometry methods such as SELDI-TOF-MS, to detect and analyze molecules directly transferred from a sample to a surface to form a molecular print of the sample. Methods and compositions of the invention can be used to produce spatially and non-spatially oriented molecular prints for detection using methods such as mass spectrometry. Methods and compositions of the invention encompass molecular printing of tissues, cells and gels onto surfaces.

Mass spectrometric detection of material transferred to a surface

Growing community of inventors

Redwood City, CA, United States of America

Fiona Lucy Plows