University of California

Fernando Soto

Joseph Wang

Liangfang Zhang

Yi Chen

Chava Angell

Berta Esteban-Fernández De Ávila

Malthe Hansen-Bruhn

Methods, systems, and devices are disclosed for intracellular payload delivery by nanomotor structures. In some aspects, a nanomotor for intracellular payload delivery includes an asymmetric body having a concave cavity at one end of the nanowire body; a functionalization layer on an outer surface of the nanowire body; and a payload substance coupled to the nanomotor by the functionalization layer in a biologically active conformation, wherein the payload substance is attached to a portion of the functionalization layer or at least partially encapsulated within the functionalization layer, in which the nanomotor is operable to propel in a biological medium and into an intracellular region of a living cell to initiate an interaction of the biologically active payload substance with an intracellular constituent of the living cell.

Growing community of inventors

La Jolla, CA, United States of America

Fernando Soto