University of California

Consejo Superior De Investigaciones Cientificas

Vivia Biotech S.l.

Fundacion Publica Andaluza Para La Investigacion De Malaga En Biomedicina Y Salud (fimabis)

Fundació Institut Mar Dtnvestigacions Mèdioues

Fernando Rodríguez De Fonseca

Daniele Piomelli

Juan Manuel Decara Del Olmo

Jesús Joglar Tamargo

Pedro Clapés Saborit

Montserrat Fito Colomer

Bruno Almeida Cotrim

Rafael De La Torre Fornell

Laura Orio Ortíz

Miguel Romero Cuevas

Magí Ferre Albaladejo

Francisco Javier Pavón Morón

Antonia Serrano Criado

María Isabel Covas Planells

Monica Alonso Scrignoli

The invention relates to the use of fatty acid amides with phenylalkylamines and of a pharmaceutical composition comprising at least one of these compounds in the prevention and/or treatment of fatty liver or a pathological condition or disease caused by fatty liver, either alcoholic or non-alcoholic, and, in particular, for the prevention and/or treatment of the alcoholic steatohepatitis or non-alcoholic steatohepatitis (NASH).

Fatty acid amides for the prevention and/or treatment of steatohepatitis

The present invention relates to the use of a compound of formula (I): or a pharmaceutically acceptable solvate or salt thereof in the preparation of a medicinal product for the prevention and/or the treatment of a disease in which the GLP-1 receptor participates or mediates, such as eating disorders or diseases, for example, obesity, anorexia, lipid dysfunction, diabetes, hyperinsulinism and cardiovascular diseases or metabolic syndrome.

1,2,4-oxadiazole derivatives as drugs modulating the GLP-1 peptide receptor

Methods, pharmaceutical compositions, and compounds for reducing body weight, modulating body lipid metabolism, and reducing food intake in mammals are provided. The compounds of the invention include fatty acid ethanolamide compounds, homologues and analogs of which the prototype is the endogenous fatty acid ethanolamide, oleoylethanolamide.

Methods, compounds, and compositions for reducing body fat and modulating fatty acid metabolism

Growing community of inventors

Málaga, Spain

Fernando Rodríguez De Fonseca