Universidad De La Frontera

Laboratorios Andromaco S.a.

Universidad Federal De Sao Paulo

Universidad De Chile

Fernando Gonzalo Romero Mejia

Antonio De Miranda

Raul Patricio Salvatici Salazar

Antonio Miranda

Raúl Sanchez Gutierrez

Eduardo Bustos Obregón

Andrés Rudolphy Fontaine

The present invention features compositions and methods for the treatment of erectile dysfunction. The compositions include substantially pure polypeptides derived from &#x3b1;-latrotoxin and can include other substances, such as pharmaceutically acceptable carriers or diluents, liposomes, hydrogels, and additional active ingredients for the treatment of erectile dysfunction. Also provided are methods, including methods for using the compositions for treatment of erectile dysfunction and in the preparation of medicaments.

Compositions and methods for treating erectile dysfunction

The present invention is directed to an active agent with contraceptive properties which corresponds to a peptide fragment of thevenom. The peptide generally includes the amino acid sequence of SEQ ID NO 2 or sequences that are at least 85% similar, obtained by chemical synthesis or through recombinant DNA technologies. Furthermore, a pharmaceutical contraceptive composition comprising the peptide fragment and one or more pharmaceutically acceptable vehicles is also described. The peptide fragment and pharmaceutical compositions are useful as a contraceptive and spermicide agent.

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Growing community of inventors

Temuco, Chile

Fernando Gonzalo Romero Mejia