Northwestern University

Fengwei Zou

Richard B Silverman

Qing Jing

Heng-Yen Wang

Soo Sung Kang

Yajuan Qin

Disclosed are compounds that are shown to inhibit the biological activity of nitric oxide synthases (NOSs). Also disclosed are pharmaceutical compositions comprising the compounds, and methods of using the compounds and pharmaceutical compositions for treating a subject in need thereof. Because the disclosed compounds are shown to inhibit the activity of nitric oxide synthases (NOSs), the disclosed compounds and pharmaceutical compositions may be utilized in methods for treating a subject having or at risk for developing a disease or disorder that is associated with NOS activity.

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Evanston, IL, United States of America

Fengwei Zou