Risen (Suzhou) Pharma Tech Co., Ltd.

Shanghai Junshi Biosciences Co., Ltd.

Shanghai Junshl Biosciences Co., Ltd.

Suzhou Radiant Photovoltaic Technology Co., Ltd

Hengtong Optic-Electric Co., Ltd.

Feng Zhou

Xianqi Kong

Jiasheng Lu

Jiamin Gu

Lin Wang

Jianrong Xu

Fei Xu

Xiang Ji

Rui Wang

Dongdong Wu

Wei Li

Gang Chen

Xiuchun Zhang

Di Wu

Xiaolin Zhang

Lecheng Zhou

Wenzhong Bao

Huiping Shi

Peidong Liu

Qiguo Zhang

Xuli Wang

Chengyong Sun

Fang Peng

Yufeng Xie

Yufeng Han

Yuliang Wang

Xiaoshan Zhang

Huaqing Fei

Jiaqing Wang

There are provided compounds of Formula I, and pharmaceutically acceptable salts and esters thereof, and pharmaceutical compositions thereof, used for inhibition or modulation of the activity of cyclin dependent kinases (CDK) and/or glycogen synthase kinase-3 (GSK-3), for the treatment of disease states or conditions mediated by cyclin dependent kinases and/or glycogen synthase kinase-3, including cancers.

Prodrugs of a CDK inhibitor for treating cancers

CD73 (also known as ecto-5'-nucleotidase) inhibitor compounds are provided, as well as compositions and uses thereof for treating or preventing CD73-associated or related diseases, disorders and conditions, including cancer- and immune-related disorders. CD73 inhibitor compounds include compounds having the structure set forth in Formula I and pharmaceutically acceptable esters or salts thereof. 

CD73 inhibitors and pharmaceutical uses thereof

There are provided compounds of Formula I, and pharmaceutically acceptable salts and esters thereof, and pharmaceutical compositions thereof, used for inhibition or modulation of the activity of cyclin dependent kinases (CDK) and/or glycogen synthase kinase-3 (GSK-3), for the treatment of disease states or conditions mediated by cyclin dependent kinases and/or glycogen synthase kinase-3, including cancers. 

Growing community of inventors

Suzhou, China

Feng Zhou