Faraday Technology Corporation

Ascentage Pharma (Suzhou) Co., Ltd.

Ascentage Pharma Group Corp Limited

Artery Technology Company

Guangzhou Healthquest Pharma Co., Ltd.

Grundfos Holding A/s

Ascentage Pharma Co., Ltd.

Grundfos (China) Holding Co. Ltd.

Feng Xu

Jianfeng Wen

Zhengxiang Wang

Meng Zhao

Ming Guo

Min-Yuan Wu

Tianzhu Wu

Yanqiong Lin

Huirong Lu

Teng Shao

Xiaoling He

Chih-Yuan Hung

Shixiong Li

Shihe Liang

Shu Dong Wu

Zhen Liang Zhang

Jiaan Huang

Wei-Tai Tsai

Shu-Dong Wu

Chiao-Wen Lo

Xingbo Ding

Zhiyong Yang

Cheng Qiao

Yanghua Cao

The present invention relates to a pharmaceutical composition containing alkynyl compound, a preparation method thereof and its application. The present invention discloses a pharmaceutical composition comprising an active pharmaceutical ingredient and an available pharmaceutical excipient; The active pharmaceutical ingredient is 3-((1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-benzamide, or its pharmaceutical acceptable salt; The available pharmaceutical excipients includes diluents and lubricants. The pharmaceutical composition can effectively improve the bioavailability of the alkynyl compound, has good dissolution and stability, and improve the drug safety.

Pharmaceutical composition containing alkynyl compound and preparation method and application thereof

An analog-to-digital converter (ADC) device equipped with a conversion suspension function and an associated operation method thereof are provided. The ADC device includes: an interleaved clock controller, arranged to generate a first clock signal and a second clock signal according to a master clock signal; and a multi-ADC circuit, coupled to the interleaved clock controller, arranged to perform analog-to-digital conversion. The multi-ADC circuit includes a first ADC and a second ADC, wherein the first ADC performs sampling and conversion operations according to the first clock signal, and the second ADC performs sampling and conversion operations according to the second clock signal. Based on the timing control of the first clock signal and the second clock signal, when any ADC of the first ADC and the second ADC is performing a sampling operation, the other ADC of the first ADC and the second ADC suspends conversion.

Analog-to-digital converter device equipped with conversion suspension function, and operation method thereof

The present invention relates to a method for preparing sulfonamides which are inhibitors of Bcl-2/Bcl-xL, comprising the compound (3R)-1-(3-(4-(4-(4-(3-(2-(4-chlorophenyl)-1-isopropyl-4-methylsulfonyl-5-methyl-1H-pyrrol-3-yl)-5-fluorophenyl)piperazin-1-yl)-phenylaminosulfonyl)-2-trifluoro methylsulfonyl-anilino)-4-phenylthio-butyl)-4-hydroxyl-piperidine, and the present invention also relates to intermediates for the preparation of the sulfonamides, a new final product and its therapeutic use, and pharmaceutical use.

Method for preparing sulfonamides drugs

A Successive Approximation Register Analog-to-Digital Converter (SAR ADC) is disclosed. The SAR ADC includes a switched capacitor array, a buffer, a comparator and a control logic circuit. The switched capacitor array is arranged to sample an input signal according to a switch control signal to generate a sampling signal. The buffer is arranged to generate a common mode voltage. The comparator is arranged to receive the sampling signal and the common mode voltage in order to generate a comparison result. The control logic circuit is arranged to generate an output signal according to the comparison result, and generate the switch control signal to control the switched capacitor array. The control logic circuit further generates an operation control signal to adjust a Miller compensation capacitor inside the buffer. An associated control method is also disclosed.

Successive Approximation Register Analog-to-Digital Converter and associated control method

A switch device including a switch circuit and switch controller. The switch circuit comprises first and second switches to selectively enable a path between an input terminal and an output terminal. The switch controller refers to a selection signal and a switch signal to respectively generate a first switch control signal at a first switch control signal output terminal and a second switch control signal at a second switch control signal output terminal. When the voltage level of an input signal at the input terminal is larger than a power voltage, the switch controller generates the first switch control signal and the second switch control signal capable of turning off the switch circuit. When the voltage level of the input signal is not larger than the power voltage, the switch controller generates the first switch control signal and the second switch control signal according to the switch signal.

Switch device with input limiting function

An analog-to-digital conversion device is provided for converting an input signal pair to generate an output signal. The analog-to-digital conversion device includes switch groups, capacitors, a comparator, and a controller. The switch groups receive the input signal pair and reference voltages, and selects to output one of the input signal pair and the reference voltages according to a control signal to generate selection voltages respectively. The capacitors receive the selection voltages respectively and generate a first comparison voltage and a second comparison voltage. The comparator compares the first comparison voltage and the second comparison voltage to generate a comparison result signal. The controller sets conversion times for converting bits of the output signal according to the comparison result signal, wherein at least two of the conversion times are different.

Analog-to-digital conversion device

An analog to digital converting apparatus and an initial method thereof are provided. The analog to digital converting apparatus includes a first and a second switching capacitor units, a circuit unit, a first and a second initialization switches, a third and a fourth capacitors and a logic buffer. The first and the second switching capacitor units respectively couple first capacitors and second capacitors to a first logic voltage, a second logic voltage or a first or a second input voltage according to a first control signal, and respectively generate a first and a second voltage. The circuit unit compares the first voltage and the second voltage to generate the first control signal. The first and the second initialization switches are respectively connected in series between the first and the second voltage and a common-mode endpoint. The logic buffer outputs the first or the second logic voltage to the common-mode endpoint.

Analog to digital converting apparatus and initial method thereof

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Suzhou, China

Feng Xu