Tarapeutics Science Inc.

Feng Ming Zou

Jing Liu

Li Wang

Cheng Chen

Xi Li

Wen Chao Wang

Ao Li Wang

Qing Song Liu

Qing Wang Liu

Chen Hu

Shuang Qi

Juan Liu

Bei Lei Wang

Wen Liang Wang

Zi Ping Qi

Zong Ru Jiang

Jiang Yan Cao

Xi Xiang Li

Provided is a novel PDGFR kinase inhibitor, comprising a compound of formula (I) or a pharmaceutically acceptable salt, solvate, ester, acid, metabolite or prodrug thereof. Further provided are use and a method of the compound of formula (I) for preventing or treating conditions associated with PDGFR kinase activity, particularly use and a method for preventing or treating conditions associated with PDGFRα and/or PDGFRβ kinase activity.

Pyrazole derivatives and use thereof

The present invention provides a novel pan-RAF kinase inhibitor, comprising a compound of formula (I) or a pharmaceutically acceptable salt, solvate, ester, acid, metabolite or prodrug thereof. The present invention also provides a use or method of the compound of formula (I) in the treatment or prevention of a disorder related to the activity of RAF and/or RAS kinase.

Pan-RAF kinase inhibitor and use thereof

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Anhui, China

Feng Ming Zou