Bioalliance C.v.

Abgenomics International Inc.

Altrubio Inc.

Feng-Lin Chiang

Shih-Yao Lin

Rong-Hwa Lin

Chiu-Chen Huang

Yu-Ying Tsai

Yu-Chi Hsieh

Shu-Hua Lee

You-Chia Yeh

Li-An Hu

Provided herein are methods of treating or preventing a T-cell mediated inflammatory disease or cancer in a subject in need thereof comprising administering to the subject a therapeutically effective amount of an antibody that specifically binds to human PSGL-1 in combination with a Janus kinase (JAK) inhibitor. In some embodiments, the T-cell mediated inflammatory disease is GVHD, e.g., acute GVHD or chronic GVHD.

Methods of using anti-PSGL-1 antibodies in combination with JAK inhibitors to treat T-cell mediated inflammatory diseases or cancers

The present disclosure provides anti-folate receptor alpha (FRA) antibody-drug conjugates comprising a hydrophilic self-immolative linker. The present disclosures further provide compositions and methods for treating cancers.

Anti-folate receptor alpha (FRA) antibody-drug conjugates and methods of using thereof

Growing community of inventors

Taipei, Taiwan

Feng-Lin Chiang