Immundiagnostik Ag

Diasys Diagnostic Systems Gmbh

Felix Walzer

Franz Paul Armbruster

Ben John

Matthias Grimmler

Pia Schu

Franz-Paul Armbruster

Tobias Becker

Thorsten Knoeller

An analyte testing system for quantifying the presence of an analyte in a speciment by lateral flow chromatography. The system comprises a test cassette () with a lateral flow chromatography and a mobile hand-held processor device () comprising a digital camera (), a source of light () and a processor (), which software and hardware () are configured to determine automatically the distance between camera and object and the measures of light in the region of interest of the lateral flow chromatography prior any retrieval of image data for further analysis and quantification of the visual signals.

System for analyzing quantitative lateral flow chromatography

An analyte testing system for quantifying the presence of an analyte in a specimen by immunochromatography. The system comprises a camera test card, depicting a test cassette () with an immunochromatography and a handheld processor device () comprising a digital camera (), a source of light () and a processor (), which software and hardware () are configured to make a pose estimation of camera and object and the measures of light in the region of interest of the immunochromatography. The system allows an automatic camera calibration and certification as a scanner for use in point-of-care diagnostics.

Calibration of a digital camera for use as a scanner

A method for measuring the presence of calprotectin (S100A8/A) heterodimer in a biological sample using a particle-enhanced turbidimetric immunoassay (PETIA) based on monoclonal antibodies. The method can be adapted on automated standard analyzers and provides a reliable clinical measurement of calprotectin in faecal samples and extracts. The method is comparable to commerical two-site sandwich ELISA. The disclosed method counters spontaneous agglutination caused by calcium ions and low-molecular weight calcium-binding S100 proteins as observed with conventional PETIAs. The method can be used for measuring the presence of human calprotectin in stool, urine, serum, plasma, synovial liquid and other body liquids. Metrological traceability and high commutability with conventional immunoassays (ELISA) has been shown despite of different measurement principles used.

Method for determination of members of the S100 family of calcium binding proteins by immunoturbidimetry

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Bensheim, Germany

Felix Walzer