Albert Einstein College of Medicine

Drexel University

The University of Manitoba

Palacky University Olomouc

Felix Kopp

Evripidis Gavathiotis

Ulrich G Steidl

Denis E Reyna

Sandhya Kortagere

Sridhar Mani

Richard N Kitsis

Dulguun Amgalan

Lorrie Kirshenbaum

Thomas P Garner

Chamini Karunaratne

Zdenek Dvorak

Activators of BAX and their uses in cancer therapy are disclosed.

BAX activators and uses thereof in cancer therapy

Compounds, compositions and method of using these compounds are disclosed for treating a disease or disorder in which it is desirable to inhibit BAX, such as a cardiovascular disease or disorder.

Small molecule BAX inhibitors and uses thereof

Small molecule agonists of the pregnane X receptor (PXR), compositions and methods are disclosed for treating or preventing gut barrier dysfunction, an illness associated with gut barrier dysfunction, toxic or inflammatory injury to intestines, or leaky intestinal (gut) syndrome in a subject.

PXR agonists and uses thereof for gut barrier dysfunction treatment and prevention

Growing community of inventors

Brooklyn, NY, United States of America

Felix Kopp