Tillotts Pharma Ag

University College London

Felipe José Oliveira Varum

Thomas Buser

Roberto Carlos Bravo Gonzaléz

Roberto Carlos Bravo González

Abdul Waseh Basit

Maxim Puchkov

Daniel Preisig

Joerg Huwyler

Esther Maria Furrer

Ana Cristina Freire

Martin Kuentz

Jan Kendall De Kruif

Carla Garofalo

Gisela Ledergerber

Vipul Yadav

Roberto Carlos Bravo GONZALÉZ

Roberto Carlos Bravo Gonzàles

Frédéric Jean-Claude Goutte

Herein described is a modified release coated capsule and a process to obtain that capsule.

Modified release coated capsules

The present invention relates to the therapeutic uses of compositions containing antibody molecules and functional fragments thereof, e.g antibody molecules and functional fragments capable of binding to tumor necrosis factor alpha (TNF&#x3b1;), in the topical treatment of inflammatory bowel diseases, including Crohn's disease and ulcerative colitis.

Topical treatment of inflammatory bowel disease using antibodies and fragments thereof

In a delayed release formulation comprising a core containing a drug and a delayed release coating for providing intestinal release, release of the drug in the colon is accelerated by including an isolation layer between the core and the delayed release coating. The delayed release coating comprises an inner layer and an outer layer. The outer layer comprises a pH dependently soluble polymeric material which has a pH threshold at about pH 5 or above. The inner layer comprises a soluble polymeric material which is soluble in intestinal fluid or gastrointestinal fluid, said soluble polymeric material being selected from the group consisting of a polycarboxylic acid polymer that is at least partially neutralised, and a non-ionic polymer, provided that, where said soluble polymeric material is a non-ionic polymer, said inner layer comprises at least one additive selected from a buffer agent and a base.

Delayed release drug formulation

The present invention relates to a modified release coated capsule and a process to obtain that capsule.

The present invention relates to a delayed release pharmaceutical formulation for delivering an active agent to the intestine, a method of preparing such formulation and the use of such formulation in the treatment of gastrointestinal disorders.

Delayed release pharmaceutical formulation and methods of making and using same

The present invention relates to microgel particles containing nanotubes loaded with an active pharmaceutical ingredient, a process for their preparation and a pharmaceutical composition comprising the same.

Microgel particles containing nanotubes loaded with an active pharmaceutical ingredient

The present invention relates to a delayed release pharmaceutical formulation for delivering an active agent to the intestine, a method of preparing such formulation and the use of such formulation in the treatment of gastrointestinal disorders, wherein the formulation includes at least one active agent associated with porous, functionalized calcium carbonate carrier particles that are surrounded by a material for colon targeting.

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Basel, Switzerland

Felipe José Oliveira Varum