Politecnico Di Milano

Omron Corporation

Fondazione Istituto Italiano Di Tecnologia

Universitá Degli Studi Di Genova

Federica Villa

Franco Zappa

Yuki Matsui

Ken Nakamuro

Rudi Lussana

Alberto Diaspro

Paolo Bianchini

Giuseppe Vicidomini

Marco Castello

Alberto Tosi

Giorgio Tortarolo

Mauro Buttafava

Colin J R Sheppard

Danilo Bronzi

Francesca Madonini

Fabio Severini

A system and method for detection, localization and signaling of single photon events and of at least two photons time coincidence events. The system includes at least one array of pixels, each of which includes a photodetector and a front-end electronics, which outputs a digital signal; at least one event detection electronics including: a plurality of digital-to-analog transducers, one for each pixel of the array, configured to convert the digital signal coming from the respective pixel in a corresponding analog signal, which is quantized in amplitude and duration; an analog adder node configured to sum the analog signals coming from the digital-to-analog transducers, obtaining a sum analog signal; and an overall analog-to-digital transducer. The system and method are ultimately configured to output a digital signal if an output signal of an analog adder node exceeds, respectively, a first threshold or the second threshold, allowing event detection, within a time window.

System and method for detection, localization and signaling of single photon events and of at least two photons time coincidence events

A distance measuring device includes a light emission portion for emitting light; a light receiving portion for receiving measurement light that is emitted by the light emission portion and reflected by a measurement object, the light receiving portion comprising a plurality of pixels, each pixel having at least one light receiving portion and outputting a light reception signal that depends on the measurement light incident on the pixel; a discrimination portion for discriminating whether the pixel receives measurement light; a pixel output control portion for selectively outputting the light reception signal of each pixel individually, depending on the determination result of the discrimination portion; and an evaluation portion for receiving the light reception signals output by the pixel output control portion and outputting a distance signal that is indicative of a distance between the measuring device and the measurement object based on these light reception signals.

Distance measuring device and distance measuring method

A distance measuring device includes a light emission portion configured to emit light; a light receiving portion configured to receive measurement light that is emitted by the light emission portion and reflected by the measurement object, the light receiving portion comprising a plurality of pixels configured to output light reception signals that depend on the received measurement light; a plurality of determination portions configured to receive the light reception signals and to determine characteristic values from the received light reception signals, and an evaluation portion that is connected to the plurality of determination portions, the evaluation portion being configured to calculate a distance from the characteristic values determined by the determination portions. Each of the plurality of determination portions is configured to receive the light reception signals only from a plurality of non-adjacent pixels.

Distance measuring device

A method for operating a point laser-scanning microscope includes scanning a sample with a focused illumination laser beam; recording a plurality of images by detecting elements being configurable to an intensity mode, in which the recorded images are intensity images g(n) related to photons collected during an entire dwell time of the illumination beam on an individual position n, or to a time-resolved mode, in which the recorded images are time-resolved images g(n, t), the collected photons being discriminated based on their arrival times to individual detecting elements; calculating a fingerprint image a by summing the plurality of intensity images g(n) over all positions n; estimating shift matrices sand sfrom the intensity images g(n); reconstructing at least one of a time-resolved object function fand an intensity object function f; and visualizing at least one of a high-resolution time-resolved image fand a high-resolution intensity image f.

Time-resolved imaging method with high spatial resolution

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Milan, Italy

Federica Villa