Health Research, Inc.

Photolitec, LLC

Farukh Durrani

Youcef M Rustum

Shousong Cao

Ravindra Kumar Pandey

Peter Kanter

Heinz Baumann

Khurshid Guru

Karoly Toth

Harry K Slocum

Erin Tracy

Joseph Cacaccio

Ravindra Cheruku

Kevin Siters

Compounds including a tetrapyrrolic or reduced tetrapyrrolic group/moiety and an epidermal growth factor receptor targeting group are disclosed. For example, a compound includes a tetrapyrrolic or reduced tetrapyrrolic group or moiety, a linker moiety, an epidermal growth factor receptor targeting group, and, optionally, a PET-active functional group. Uses of the compounds, for example, methods of treating a hyperproliferative tissue in an individual, and kits including one or more of the compounds are also provided.

Epidermal growth factor receptor (EGFR) targeted photosensitizers

The present invention discloses a method for reducing alopecia and bladder toxicity associated with the anti-cancer agent cyclophosphamide. The method comprises administering to an individual, in need of such a treatment, cyclophosphamide and a selenium compound. The selenium compounds may be administered before, during or after administration of the anti-cancer agent.

Method of reducing alopecia and bladder toxicity of cyclophosphamide

The present invention discloses a method for enhancing the efficacy of anti-cancer agents. The method comprises administering to an individual, in need of such a treatment, an anti-cancer agent and a selenium compound. The selenium compounds may be administered before, during or after administration of the anti-cancer agent.

Method of reducing toxicity of anticancer agents

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Snyder, NY, United States of America

Farukh Durrani