King Abdulaziz University

Farid Ahmed

Abdelsattar Mansour Omar

Moustafa Elsayed El-Araby

Azizah M Malebari

Martin K Safo

Maan Talaat Khayat

Dhaval Shah

Ashraf B Abdel-Naim

Ahmed Esmat

Thikryat Neamatallah

Muhammad Hussain Al-Qahtani

Syed Kashif Zaidi

Md Nasrul Hoda

Heba Al Khatabi

Therapeutic compounds containing a phenyl core and amide link(s). Also described are pharmaceutical compositions incorporating the therapeutic compounds and a method for treating cancer with the compounds. These compounds are cytotoxic to stomach, colon, breast, and leukemia cancer cell lines via dual inhibition of Src kinases and tubulin.

Method for treating stomach cancer

Method for treating a patient having a colon cancer

Stroke patients with comorbidities, such as diabetes, hypertension, or other conditions associated with cardiovascular, pulmonary or renal disease do not respond well to current treatments for stroke. An inhibitor of S-nitrosoglutathione reductase (GSNOR) is administered as an adjunct therapy with remote ischemic conditioning (RIC) to treat a stroke in a subject having at least one comorbidity, such as diabetes and hypertension. When performed in conjunction with GRI therapy and RIC, intravenous tissue plasminogen activator therapy (IVT) for thrombolysis and/or endovascular thrombectomy (EVT) for clot retrieval are effective in subjects with comorbidities, even after five hours post-onset of stroke.

GSNO reductase inhibitor as an adjunct therapy with remote ischemic conditioning and thrombolytic reperfusion therapies in stroke

Cytotoxic compounds containing a phenyl core, amide link(s), an imidazolinone or a propenamide moiety. Also described are pharmaceutical compositions incorporating the cytotoxic compounds and methods for treating cancer. These compounds are cytotoxic against breast, prostate, and leukemia cancer cell lines via dual inhibition of Src kinases and tubulin.

Chemotherapeutic oxazolone derivatives and pharmaceutical compositions thereof

Method for making anti-cancer compounds

Anticancer compounds, pharmaceutical compositions thereof, and a method of treating cancer

Anti-cancer compounds having oxazolone derivation

Pharmaceutical composition for treating cancer

Method for treating a patient having cancer

Cytotoxic compounds, pharmaceutical compositions thereof, and methods of treating cancer

Amide group-containing compounds and use for cancer treatment

Pharmaceutical composition and method of treating cancer

Growing community of inventors

Jeddah, Saudi Arabia

Farid Ahmed