University of Sharjah

Farah Ibrahim Al-Marzooq

Taleb H Altel

Raafat A El-Awady

Hany A Omar

Srinivasulu Vunnam

Vunnam Srinivasulu

Shifaa Abdin

Amin Majdalawieh

Amjad Ali

Mohamad Hamad

Mawieh Hamad

Imad Abu Yousef

There is provided novel anticancer and antibacterial compounds, pharmaceutically acceptable salts thereof, and processes for their preparation. The compounds have anticancer activity, which results in the reduction of tumour cell proliferation, enhances cancers cells apoptosis and regulation of iron signalling. The compounds are also particularly active against various Gram-negative and Gram-positive multidrug-resistant bacteria, such as extended-spectrum beta-lactamase (ESBL) producing and colistin-resistant, carbapenem-resistant, carbapenem-resistant, and methicillin-resistant(MRSA) including those with reduced susceptibility to many control antibiotics.

Nature-inspired anticancer and antibacterial motifs and pharmaceutical composition thereof

Novel heterocyclic fused systems are disclosed herein which possess numerous biological activities, including but not limited to antibacterial activity, and usefulness to the treatment of many disease states, such as pathogenic infections. In particular, new imidazoles are disclosed along with related processes of preparation and methods of use as antibacterial agents. The disclosed compounds were found to be active against several Gram-positive bacteria, includingand, and were also found to be active against several species of multi-drug resistant, such as, and

Heterocyclic systems and pharmaceutical applications thereof

Growing community of inventors

Sharjah, United Arab Emirates

Farah Ibrahim Al-Marzooq