Zhejiang Academy of Traditional Chinese Medicine

Fanzhi Kong

Yongzhou Hu

Xia Liu

Wanping Zhu

Yuji Wang

The present invention discloses a terpinenol compound as well as its preparation method and application. The structure of such terpinenol compound is as shown in Formula (I) or (II). In Formula (I), R is independently selected from C-Calkyl, &#x2014;NRR, &#x2014;SRor &#x2014;OR; R, R, Rand Rare independently selected from C-Calkyl or &#x2014;NO; the C-Calkyl can be substituted by OH; Alternatively, the Rand Rform a five-member ring or six-member ring in together with N used to link up them; the five-member or six-member ring may contain one O or C&#x2550;O. As indicated by results of activity test, such terpinenol compound has satisfactory effect in prevention of asthma, inflammation and pulmonary artery hypertension, which also has high pharmaceutical significance. 

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Hangzhou, China

Fanzhi Kong