Medidata Solutions, Inc.

Fanyi Zhang

Michael Elashoff

Hrishikesh Karvir

Jingshu Liu

Christopher Bound

A system for predicting subject enrollment for a study includes a time-to-first-enrollment (TTFE) model and a first-enrollment-to-last-enrollment (FELE) model for each site in the study. The TTFE model includes a Gaussian distribution with a generalized linear mixed effects model solved with maximum likelihood point estimation or with Bayesian regression, and the FELE model includes a negative binomial distribution with a generalized linear mixed effects model solved with maximum likelihood point estimation or with Bayesian regression estimation.

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Jersey City, NJ, United States of America

Fanyi Zhang