Nanjingjinsirui Science & Technology Biology Corporation

Schering Corporation

Genscript Holdings (Hong Kong) Limited

Nanjing Legend Biotech Co., Ltd.

Genscript Hongkong

Jinsite Science & Technology (Nanjing) Co., Ltd.

Nanjing Legend Biotech., Ltd.

Fang Liang Zhang

Zhuying Wang

Tao Bai

Jason Samuel Simon

Nicholas J Murgolo

Ying Jiang

Lin Luo

Shu Wu

Tao Wang

Jianbing Zhang

Weiqiang Liu

Ping Yang

Wenzhu Chen

Hong Qian

Xin Chen

Xiaowu Liu

Luquan Wang

Yun He

Chunjiao Wang

Jinyu Yang

Zhibing Liu

Fanli Meng

Tianhui Xia

Bing Lai

Hongfei Ren

Zhan Dai

Novel antibodies, such as single domain antibodies (sdAbs), or fragments thereof that specifically bind a transferrin are described. Compositions, methods and systems for increasing the half-life of a target protein in a serum using an antibody or fragment thereof against a transferrin are described.

Compositions and methods for increasing protein half-life in a serum

An improved staining method and system is described for staining a biopolymer such as a peptide, a protein, an RNA, a DNA, an oligosaccharide or a complex containing a peptide, a protein, an RNA, a DNA, or an oligosaccharide in a matrix. The method includes the step of moving a staining reagent into the matrix using an electric force. The staining time can be dramatically reduced relative to conventional technologies. The improved staining method can particularly be used, for example, to stain proteins after gel separation. Other related methods, related kits and related systems for carrying out the staining method are also described.

System for rapid electrophoresis binding method and related kits and compositions

An improved staining method is described for staining a biopolymer such as a peptide, a protein, an RNA, a DNA, an oligosaccharide or a complex containing a peptide, a protein, an RNA, a DNA, or an oligosaccharide in a matrix. The method includes the step of moving a staining reagent into the matrix using an electric force. The staining time can be dramatically reduced relative to conventional technologies. The improved staining method can particularly be used, for example, to stain proteins after gel separation. Other related methods and related kits are also described.

Rapid electrophoresis binding method and related kits and compositions

Methods and compositions for cloning a donor DNA molecule into an acceptor vector at a predetermined location are described. The methods are based on homologous recombination mediated by in vitro treatment of the donor DNA and the acceptor vector with an enzyme cocktail containing an exonuclease and a single-stranded DNA binding protein.

Homologous recombination-based DNA cloning methods and compositions

Homologous recombination-based DNA cloning compositions

The present invention provides improved and rapid detection methods for an antigen such as a chemical compound, a peptide, a nucleic acid, or a protein released from cells or virus particles in situ. The detection time for an antigen can be dramatically reduced relative to conventional technologies. The technology can particularly be used, for example, to modify and reduce the detection time significantly in traditional ELISA, and also Western blot or Dot blot assays. The improved ELISA method is rapid, economical, reproducible, simple and automatable. Also provided are compositions and kits for using the improved ELISA methods for the rapid detection of antigens.

Composition related to rapid ELISA process

An improved gene sequence optimization method, the systematic optimization method, is described for boosting the recombinant expression of genes in bacteria, yeast, insect and mammalian cells. This general method takes into account of multiple, preferably most or all, of the parameters and factors affecting protein expression including codon usage, tRNA usage, GC-content, ribosome binding sequences, promoter, 5'-UTR, ORF and 3&#x2032;-UTR sequences of the genes to improve and optimize the gene sequences to boost the protein expression of the genes in bacteria, yeast, insect and mammalian cells. In particular, the invention relates to a system and a method for sequence optimization for improved recombinant protein expression using a particle swarm optimization algorithm. The improved systematic optimization method can be incorporated into a software for more efficient optimization.

Method of sequence optimization for improved recombinant protein expression using a particle swarm optimization algorithm

The present invention relates to RF-amide peptides and their use for treating, preventing and curing neurological and metabolic medical disorders. The invention also relates to methods for modulating a G-protein coupled receptor and for identifying substances which modulate the receptor.

Antibodies and functional fragments thereof that specifically bind an RF-amide peptide or a precursor thereof

Rapid ELISA processes and related compositions

Rapid C-ELISA process and related compositions

G-protein coupled receptor ligands and methods

Growing community of inventors

Fanwood, NJ, United States of America

Fang Liang Zhang