University of Michigan

Fan Wu

Euisik Yoon

Mary-Ann Mycek

James M Scheiman

William Lloyd

Seung Yup Lee

A system for analyzing tissue includes a platform and an optical sensing unit coupled to the platform. The optical sensing unit has a detector and a plurality of light sources surrounding and electrically isolated from the detector. The optical sensing units obtain optical data for tissue analysis.

System for analyzing tissue

A neural probe () is provided for in vivo communication with biological tissue, including stimulating neurons and/or recording neural electrical activity. The probe () may be constructed so that the immune response by the biological tissue in which the device is implanted is reduced over known implantable probes. The probe () can be constructed with a tip () that has a branched configuration, with electrodes () located along each of the branches (). A biodegradable coating () is disposed over at least the tip () of the probe () to provide the probe () with sufficient integrity for insertion into the biological tissue and to degrade after insertion. The biodegradable coating () can have an anti-inflammatory drug or other bioagent distributed therein for localized release of the bioagent to further reduce the immune response.

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Greenbelt, MD, United States of America

Fan Wu