Smartdyelivery Gmbh

Falk Gonnert

Michael Bauer

Peter Recknagel

Ulrich Sigmar Schubert

Michael Gottschaldt

Anja Trager

Christian Pietsch

Adrian Press

Ulrich Schubert

The invention relates to a nanostructured delivery system comprising at least one polymer and/or at least one lipid and at least one polymethine dye, wherein the at least one polymethine dye acting as a targeting unit brings about the targeted transport of the nanostructured delivery system into a target issue. The invention also relates to a pharmaceutical composition and the uses of the nanostructured delivery system for transporting said system and, optionally, a pharmaceutical active ingredient into the target tissue, as well for treating liver and/or kidney diseases.

Cell-specific targeting using nanostructured delivery systems

The invention relates to a method for acquiring data in order to determine organ function, in particular the liver or kidney function, comprising one or more polymethine fluorescent dyes having a fluorescence emission maximum, measured in ethanol, of less than or equal to 820 nm, and to the use of dyes as markers for acquiring data in order to determine the organ function. The invention further relates to a kit for determining an organ function with a marker dye, and to a device for acquiring data in the method.

Measurement method for determining an organ function

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Jena, Germany

Falk Gonnert