Acadia Pharmaceuticals Inc.

Fabrizio Badalassi

Roger Olsson

Nathalie Schlienger

Mikkel Boas Thygesen

Birgitte Winther Lund

Jan Pawlas

Rasmus Lewinsky

Alma Fejzic

Disclosed herein is a novel class of aminophenyl compounds having the structure: wherein Ris cyano or nitro and ring A is a bi- or tricyclic bridged heterocycle and to their use as modulators of androgen receptor for the treatment or prevention of conditions relating thereto.

Aminophenyl derivatives as selective androgen receptor modulators

Disclosed herein are bicycloaryl compounds of Formula (I) that selectively modulate nuclear receptors, preferably the androgen receptor, or a pharmaceutically acceptable salt, ester, amide, or prodrug thereof, and methods of treating disease comprising administering a compound of Formula (I) to a patient in need thereof.

Androgen receptor modulators and method of treating disease using the same

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Copenhagen, Denmark

Fabrizio Badalassi