Dsm IP Assets B.v.

Roche Vitamins Inc.

Fabrice Aquino

Werner Bonrath

Johannes Tschumi

Thomas Netscher

Rolf Kuenzi

Max Hugentobler

Alexander Radspieler

Patrick Bohrer

Aljosa Crevatin

The present invention is related to a novel and improved process for the production of dehydrolinalyl acetate (DLA), which IUPAC name is acetic acid 1-ethynyl-1,5-dimethyl-hex-4-enyl ester, starting from dehydrolinalool (DLL), which IUPAC name is 3,7-dimethyloct-6-en-1-yn-3-ol, by acetylation.

Process of production of dehydrolinalyl acetate (II)

The present invention is related to a novel and improved process for the production of dehydrolinalyl acetate (DLA), which IUPAC name is acetic acid 1-ethynyl-1,5-dimethyl-hex-4-enyl ester, starting from dehydrolinalool (DLL), which IUPAC name is 3,7-dimethyloct-6-en-1-yn-3-ol, by catalytic acetylation.

Process of production of dehydrolinalyl acetate (I)

A process for the manufacture of gamma-delta-unsaturated ketones of formula (R)(R)C&#x2550;CH&#x2014;CH&#x2014;CH&#x2014;CO&#x2014;R(I), wherein Ris methyl or ethyl; Ris a saturated or unsaturated linear or cyclic hydrocarbon residue and Ris methyl or ethyl, by reacting a tertiary vinyl carbinol of formula (R)(R)C(OH)&#x2014;CH&#x2550;CH(II) with an isopropenyl methyl or ethyl ether of formula HC&#x2014;C(OR)&#x2550;CH(III) in the pre-sence of an ammonium salt as catalyst.

Manufacture of gamma-delta-unsaturated ketones

A process for the preparation of ubihydroquinones and ubiquinones by condensation of a prenol or isoprenol with a hydroquinone or derivative thereof in the presence of 0.005-1.0 mol % of a catalyst which is a Broensted-acid, a Lewis-acid from the group consisting of a derivative of Bi or In or an element of group 3 of the periodic table of the elements, a heteropolyacid, an NH&#x2014; or a CH-acidic compound, and optionally oxidizing the ubihydroquinone obtained.

Process for the preparation of ubihydroquinones and ubiquinones

Methylheptenone (2-methyl-2-hepten-6-one) is prepared by reacting 2-methyl-3-buten-2-ol with isopropenyl methyl ether in the presence of hydrogen tris(oxalato)phosphate or hydrogen bis(oxalato)borate.

Process for the preparation of methylheptenone

A process for the manufacture of d,l-&agr;-tocopherol by the acid-catalyzed condensation of trimethylhydroquinone with isophytol or phytol in ethylene or propylene carbonate or a mixture of both carbonates, or in a mixture of one or both of the carbonates and a non-polar solvent, comprises carrying out the condensation in the presence of at most 0.4 weight percent based on the weight of isophytol or phytol of 12-tungstophosphoric acid, 12-molybdophosphoric acid or 12-tungstosilicic acid. The product of the process is the most active and industrially important member of the vitamin E group.

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Reiningue, France

Fabrice Aquino