Her Majesty the Queen in Right of Canada, as Represented by the Minister of Agriculture and Agri-Food

Other

Her Majesty the Queen in Right of Canada as Represented by the Ministerof Agriculture and Agri-Food Canada

F William Collins

A Bachir Sarr

David A Fielder

Mark James Redmond

Bruce J Holub

Robert Z D'Attilio

David Fielder

Dominique P Bureau

Diana J Philbrick

A process is described for the preparation f electrostatically-linked, aliphatic- or alicyclic-substituted anionic or cationic polysaccharide gels from readily available macroporous ionic polysaccharide chromatographic media, such as diethylaminoethyl (DEAE), quaternary aminoethyl (QAE) and sulfopropyl (SP) substituted polysaccharide gels. These novel gels are used for the isolation, recovery and purification of non-polar extractives using one or more extracting solvents from the group of lower alcohols, ketones, and water. The non-polar extractives may be alk(n)lyresorcinols, steroid, triterpenoid, cardiac glycosides and saponins, steryl ferulates and other phenolic acid conjugates, flavonoids, lipids, alcohol-soluble antimicrobials, prolamines or other alcohol-soluble proteolipid complexes.

Methods for the isolation, recovery and purification of non-polar compounds using novel hydrophobically-modified polysaccharide gels

A method of treating polycystic kidney disease is described. The method involves administering soyasaponin B to an animal in need thereof.

Triterpene saponins from soybeans for treating kidney disease

Preparation of novel gels for the purification of non-polar extractives

A process is described for the isolation, recovery and purification of non-polar extractives using one or more extracting solvents from the group of lower alcohols, ketones, and water. The non-polar extractives may include one or more of the classes alk(en)lyresorcinols, steroid, triterpenoid and cardiac glycosides and saponins, steryl ferulates and other phenolic acid conjugates, flavoroids, polar lipids, alcohol-soluble antimicrobials, prolamines and other alcohol-soluble proteolipids complexes. The process uses an aliphatic-substituted polysaccharide gel matrix in a process of hydrophobic interaction chromatography, and involves the steps of absorption, washing and recovery, wherein the extractives are absorbed and desorbed in the presence of and as a result of the concentration and selection of the organic ste of regenerating the gel matrix for further use.

Process for the isolation, recovery and purification of non-polar extractives

Growing community of inventors

Ottawa, Canada

F William Collins