Enichem S.p.a

Ministero Dell'universita E Della Ricerca Scientifica E Tecnologica

Istituto Guido Donegani S.p.a.

Ministero Dell 'universita'e Della Ricerca Scientifica E Technologica

Metapontum Agrobios S.c.r.l.

Ezio A Battistel

Daniele Bianchi

Pietro Cesti

Giuliana Franzosi

Roberto Tassinari

Rossella Bortolo

Rodolfo Vignola

Vilhelmus Van Der Goes

Giampietro Borsotti

Mirella Pilone

Francesco Cellini

Sandro Spezia

Carlo Pina

Rina Iannacone

Silvana Bonicelli

Process for the synthesis of diricinoleyphosphatidylcholine

The invention relates to a process for the hydroxylation of aromatic hydrocarbons by direct oxidation with hydrogen peroxide. The process is carried out in the presence of a catalyst comprising:

Process for the hydroxylation of aromatic hydrocarbons

7-amino-cephalosporanic acids having the formula ##STR1## are obtained by submitting compounds having the following formula to enzymatic conversion: ##STR2## wherein R represents H, OH, O--CO--R', R' being an alkyl radical with from 1 to 4 carbon atoms, R.sup.1 represents a carboxylic group. The reaction is carried out in the presence of a microorganism selected from the Pseudomonas, Bacillus, Achromobacter genera, or in the presence of an enzyme, either free or immobilized, derived therefrom.

Process for the enzymatic preparation of 7-amino-cephalosporanic acids

A process is described for the separation of the optical isomers of alphayl- or alpha-aryloxy- carboxylic acids by means of the stereoselective hydrolysis of racemic alkyl esters of the above acids in the presence of bacteria or their enzymes, selected from the species Brevibacterium, Bacteridium, Micrococcus, and Bacillus.

Process for the enzymatic separation of the optical isomers of

The enzymatic preparation of cephalosporanic derivatives, or their salts, ving the formula: ##STR1## wherein R is --CO--COOH or --COOH, R.sub.1 is H, OH, or --O--CO--R' and R' is an alkyl group with 1 to 4 carbon atoms, is carried out by the oxidative deamination of compounds, or their salts, having the formula: ##STR2## with an oxidase D-Aminoacid enzyme derived from Rhodotorula glutinis NCIMB 40412. The enzyme can be in a free or immobilized form.

Process for the enzymatic preparation of cephalosporanic derivatives

Continuous biotechnological preparation of optical isomer S(+) of 2-(6-methoxy-2-naphthyl) propionic acid consisting in the reaction of a racemic (R,S) ester of 2-(6-methoxy-2-naphthyl) propionic acid having melting point below 50.degree. C. of formula: ##STR1## wherein R.sub.1 =a C.sub.2 -C.sub.10 alkyl, C.sub.4 -C.sub.6 cycloalkyl, phenyl, tetrahydropyranyl , tetrahydrofuranyl radicals and

Process for the continuous biotechnological preparation of optical

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La Spezia, Italy

Ezio A Battistel