University of Minnesota

Eyup Akgun

Philip S Portoghese

Carolyn Ann Fairbanks

George Latimer Wilcox

Daniel John Bruce

The invention provides compounds, compositions, and methods for treating pain.

Combination for treating pain

and salts thereof are disclosed. Also disclosed are pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods using a compound of formula I.

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Minneapolis, MN, United States of America

Eyup Akgun