Avedro, Inc.

Cynosure, Inc.

Cognoptix, Inc.

Neuroptix Corporation

Evan Sherr

Marc David Friedman

David Muller

Pavel Kamaev

Stephen D Fantone

David Usher

James Henry Boll

Norman C Ford

Lee E Goldstein

Leo T Chylack, Jr

Ronald Scharf

Paul D Hartung

Radha Pertaub

Rafael Armando Sierra

George E Cho

Satish Herekar

Eric Calvin Koschmann

Joseph M Day

Jamie Koufman

William Eddington

Sara Rood-Ojalvo

Steven D Fantone

Sarah M Peterson

Leo T Chylack

Devices and approaches for monitoring time based photo active agent delivery or photo active marker presence in an eye. A monitoring system is provided for measuring the presence of a photo active marker by illuminating the eye so as to excite the photo-active marker and then observing characteristic emission from the photo active marker. Example systems incorporate Scheimpflug optical systems or slit lamp optical systems to observe cross sectional images of an eye to monitor instantaneous distribution, diffusion pattern, and rate of uptake of a photo active agent applied to an eye. Systems and methods further allow for utilizing the monitored distribution of photo active agent in the eye as feedback for a cross-linking system.

Systems and methods for monitoring time based photo active agent delivery or photo active marker presence

A method for controlling activation of Riboflavin applied to an eye includes applying the Riboflavin to a selected region of a cornea of the eye and initiating cross-linking activity in the selected region by activating the Riboflavin with pulsed light illumination. The pulsed light illumination has an irradiance, dose, and an on/off duty cycle. The irradiance, the dose, and the on/off duty cycle are adjusted in response to a determination of photochemical kinetic pathways for Riboflavin cross-linking activity and to control photochemical efficiency.

Systems and methods for corneal cross-linking with pulsed light

A system for performing quasi-elastic light scattering and fluorescent ligand scanning on a subject's eye includes a light source configured to transmit light toward the subject's eye, a lens configured to focus light sent from the source and scattered by the subject's eye, a measurement reflector disposed to receive at least a portion of the focused light and configured to reflect a first portion of the received light, a camera configured and disposed to receive the first portion of the received light and configured to provide indicia of an image corresponding to the first portion of the received light, and a processor coupled to the camera and configured to analyze intensities of light in the image to determine a location of a reference point corresponding to an interface of a portion of the eye.

Ocular imaging

Lasers capable of lasing at at least two wavelengths are provided having a lasing medium which is capable of lasing at a first wavelength and at a second wavelength. Also disclosed are laser workstations having two lasers driven by a single electronics drive system in which a single energy storage network is connected to a first laser pump chamber operative to excite a first laser medium and connected to a second laser pump chamber operative to excite a second laser medium.

Multiple wavelength laser workstation

Apparatus for the treatment of Barrett's esophagus, including: an inflatable balloon for insertion into the esophagus, an endoscope for passing inside the balloon on a distal end thereof, a laser fiber apparatus for insertion within the balloon in the esophagus, and a balloon inflation/deflation means in fluid communication with the balloon for inflating and emptying the balloon into and out of contact with the walls of the esophagus to be treated. The balloon may occlude the stomach from the esophagus during treatment.

Esophageal lesion treatment method

Growing community of inventors

Ashland, MA, United States of America

Evan Sherr