Sanifit Therapeutics S.a.

Laboratorios Sanifit, S.l.

Numat Biomedical, S. L.

Laboratoris Sanifit, S.l.

Eva Martin Becerra

Joan Perello Bestard

Bernat Isern Amengual

Fernando Tur Espinosa

Maria De Mar Benito Amengual

Paula Mendoza De Las Heras

Irene Lentheric

Ciriaco Maraschiello De Zuani

Eva Tur Tur

Maximo Encabo Alarcon

Marta Monjo Cabrer

Joana Maria Ramis Morey

Maria Del Arriero Sanchez

Ruben Henriquez Palaez

The present invention relates to method for the direct detection and/or quantification of at least one compound with a molecular weight of at least 200, wherein the compound to be detected and/or quantified is a chemically complex molecule, wherein said chemically complex molecule is substituted with at least two groups R, wherein each R group means independently —OH, —OP(O)(OH)2 or —P(O)(OH)2, with the proviso that at least two R are independently selected from —P(O)(OH)2 and —OP(O)(OH)2, wherein the compound or compounds to be detected and/or quantified are within a biological matrix, wherein said biological matrix is a biological fluid, a biological tissue, stomach contents, intestine contents, stool sample or a culture cells, wherein the method comprises performing a chromatography and identifying the retention time and/or the intensity of the signal by means of a mass or radioactivity detector.

Method for the direct detection and/or quantification of at least one compound with a molecular weight of at least 200

The present invention relates to method for the direct detection and/or quantification of at least one compound with a molecular weight of at least 200, wherein the compound to be detected and/or quantified is a chemically complex molecule, wherein said chemically complex molecule is substituted with at least two groups R, wherein each R group means independently &#x2014;OH, &#x2014;OP(O)(OH)2 or &#x2014;P(O)(OH)2, with the proviso that at least two R are independently selected from &#x2014;P(O)(OH)2 and &#x2014;OP(O)(OH)2, wherein the compound or compounds to be detected and/or quantified are within a biological matrix, wherein said biological matrix is a biological fluid, a biological tissue, stomach contents, intestine contents, stool sample or a culture cells, wherein the method comprises performing a chromatography and identifying the retention time and/or the intensity of the signal by means of a mass or radioactivity detector.

The present invention relates to method for the direct detection and/or quantification of at least one compound with a molecular weight of at least 200, wherein the compound to be detected and/or quantified is a chemically complex molecule, wherein said chemically complex molecule is substituted with at least two groups &#x2014;R, wherein each R group means independently &#x2014;OH, &#x2014;OP(O)(OH)2 or &#x2014;P(O)(OH)2, with the proviso that at least two R are independently selected from &#x2014;P(O)(OH)2 and &#x2014;OP(O)(OH)2, wherein the compound or compounds to be detected and/or quantified are within a biological matrix, wherein said biological matrix is a biological fluid, a biological tissue, stomach contents, intestine contents, stool sample or a culture cells, wherein the method comprises performing a chromatography and identifying the retention time and/or the intensity of the signal by means of a mass or radioactivity detector.

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Palma De Mallorca, Spain

Eva Martin Becerra