Trizell Limited

Eva Kristiina Rasanen

Minna Kristiina Karhinen

Piia Kristiina Valonen

Tarja Hannele Tuunanen

Seppo Yla-Herttuala

Hanna P Lesch

Seppo Ylä-Herttuala

Milla Jonna Karoliina Karnaattu

Achim Muller

We have modified a commercially-available adherent cell culture bioreactor in several ways to increase productivity of cultured cells, while decreasing contamination risk. We found that modifying a commercially-available adherent cell culture bioreactor to provide for slower cell culture medium flow unexpectedly and dramatically increases the productivity of the cultured adherent cells. We also developed a new sampling manifold configuration and new way of taking samples, to reduce contamination risk.

Method of manufacturing a recombinant polypeptide

Fixed-bed bioreactor with constant-flow pump / tubing system

We have modified a commercially-available adherent cell culture bioreactor, developing a new sampling manifold configuration and new way of taking samples to reduce contamination risk.

Aseptic bioreactor sampling system

Growing community of inventors

Hiltulanlahti, Finland

Eva Kristiina Rasanen