Albert-Ludwigs-Universitaet Freiburg

Greenovation Biotech Gmbh

Universitaet Fuer Bodenkultur Wien

Albert-Ludwigs-Universitat Freiburg

Universitat Fur Bodenkultur Wien

Eva Decker

Ralf Reski

Gilbert Gorr

Friedrich Altmann

Christian Stemmer

Otmar Lienhart

Anna Koprivova

Manuela Graf

Juliana Parsons

Johannes Stadlmann

The field of the invention relates to a method for the production of a recombinant protein in a plant-based system comprising the steps of providing a plant-based system comprising a modulation for a plant endogenous prolyl-4-hydroxylase gene, delivering a gene encoding the recombinant protein into the plant-based system, and cultivating the plant-based system for the expression of the gene encoding the recombinant protein. The field of the invention further relates to a recombinant protein, which has been produced in a plant-based system. A plant-based system and use of the recombinant protein are also provided.

Modified expression of prolyl-4-hydroxylase in physcomitrella patens

Bryophyte plants and bryophyte plant cells comprising dysfunctional fucT and xylT genes and an introduced glycosyltransferase gene, methods for the production of glycosylated proteins therewith, vectors and uses thereof.

Transformed bryophyte cell having disrupted endogenous alpha 1,3-fucosyl and beta 1,2-xylosyl transferase encoding nucleotide sequences for the production of heterologous glycosylated proteins

Growing community of inventors

Freiburg, Germany

Eva Decker