Highland Innovations Inc.

Asta, Co. Ltd.

Eung Joon Jo

Yohahn Jo

Embodiments relate to an apparatus, method, or computer program. A laser may be configured to irradiate a plurality of laser pulses on a target area to ionize a sample placed in the target area into at least one ionized particle. Electrodes at a first end of a flight tube may be configured to accelerate ionized particles into the flight tube. A detector at a second opposite end of the flight tube may independently measure a time of flight of the ionized particles through the flight tube and an intensity of the ionized particles.

Shot-to-shot sampling using a matrix-assisted laser desorption/ionization time-of-flight mass spectrometer

A disease diagnostic system where a sample preparation unit and/or a matrix-assisted laser desorption/ionization time-of-flight mass spectrometer (MALDI-TOF MS) data generation unit may be integrated in one system or a set of a system to improve the user-friendliness of the system. The system may include a sample preparation unit with processing modules and/or a handler to move samples in an autonomous manner to enhance reproducibility of measurement data and/or user-friendliness. A different set of processing modules may be selected for a particular disease type (e.g. such as cancer) to be diagnosed. The system may be used to identify biomaterials such as bacteria, virus, and fungi from body fluids like blood, urine, and saliva and other cells.

Integrated disease diagnostic system using matrix-assisted laser desorption/ionization time-of-flight mass spectrometer

Methods, systems, apparatuses, and/or computer programs. Mass spectrometer test data (e.g. a blood sample of a medical patient) may be associated with metadata information. The associated metadata information may be associated with the medical patient. A subset of a sample reference library may be based on the associated metadata information. The sample reference library may include a plurality of sets of mass spectrometer reference data, in accordance with embodiments. Embodiments match the mass spectrometer test data with mass spectrometer reference data of the selected subset of the sample reference library. Embodiments determine characteristic information of a source of the mass spectrometer test data (e.g. the medical patient) based on the known characteristics of the matched mass spectrometer reference data.

Categorization data manipulation using a matrix-assisted laser desorption/ionization time-of-flight mass spectrometer

An apparatus, method, or computer program. spectrometer test data of a sample may be received for processing. The spectrometer test data may include time-of-flight data in units of time and intensity of ionized particles travelling through a flight tube. The spectrometer test data may be matched to a reference library to determine characteristic information of the sample. The reference library may include spectrometer sample data in units of time and intensity of ionized particles of pre-stored reference samples detected by spectrometers in the past. The spectrometer reference data has known characteristics that the matching associates with the received spectrometer test data.

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Old Tappan, NJ, United States of America

Eung Joon Jo