Aeon Medix Inc.

Yungjin Pharm Co., Ltd.

Yungjin Pharmaceutical Co., Ltd.

Eun Young Lee

Yong Song Gho

Yoon Keun Kim

Sung Wook Hong

Ji Hyun Kim

Seng Jin Choi

Bok Sil Hong

Yu Sun Kim

Jun Pyo Choi

Young Koo Ji

Eun Jeong Choi

Eun Jung Choi

The present disclosure relates to a method of assessing a subject's susceptibility to a vascular disease. The method may comprise providing a concentrated population of extracellular vesicles contained in a biological material obtained from a subject, processing the concentrated population to determine if the concentrated population contains a 16S rRNA sequence of, and upon determining that the concentrated population contains a 16S rRNA sequence of, further determining that the subject is potentially susceptible to a vascular disease.

Extracellular vesicles derived from Gram-positive bacteria, and use thereof

The present application relates to extracellular vesicles (EVs) derived from gram-positive bacteria. In detail, the present application provides animal models of disease using extracellular vesicles derived from gram-positive bacteria, provides a method for screening an active candidate substance which is capable of preventing or treating diseases through the animal models of disease, provides vaccines for preventing or treating diseases caused by extracellular vesicles derived from gram-positive bacteria, and provides a method for diagnosing the causative factors of diseases caused by gram-positive bacteria using extracellular vesicles.

Extracellular vesicles derived from gram-positive bacteria, and use thereof

The present application relates to a composition comprising extracellular membrane vesicles derived from indoor air. In addition, the present application provides a method for diagnosing, preventing and/or treating an inflammatory respiratory disease, lung cancer and the like using the extracellular membrane vesicles. In detail, the present application involves injecting extracellular membrane vesicles present in indoor air into an animal in order to prepare an animal respiratory disease model, and enables the search and/or discovery of drug candidates for preventing or treating respiratory diseases using the animal model. The present application provides a vaccine for preventing and/or treating respiratory diseases, to a method for diagnosing substances causing respiratory diseases, and to a method for inhibiting the activities of extracellular membrane vesicles in indoor air or removing the extracellular membrane vesicles from indoor air so as to prevent the occurrence and exacerbation of respiratory diseases.

Composition comprising extracellular membrane vesicles derived from indoor air, and use thereof

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Pohang-si, South Korea

Eun Young Lee