Newgex Inc.

Prostemics Co. Ltd.

Neurogenex Co., Ltd.

Eun-Wook Choi

Dong-Seung Seen

Kyung-jin Kim

Neon-C Jung

Ho-Sun Son

Min-Sung Kim

Sang-Wook Park

Won-Jong Lee

Tae-Gyu Lee

Anthony D Kang

Jong-Bae Seo

Jung-Hee Shin

Yong-Weon Yi

Min-Koo Seo

Eun-Jung Choi

Ji-Ung Maeng

Eun-Joo Park

Do-Hui Kim

Sun-Mi Choi

Seong-Yeol Ko

Jac-Yong Park

Young-Shik Choi

The present invention provides a method for ameliorating or treating inflammatory bowel disease (IBD) and/or irritable bowel syndrome (IBS), comprising administering extracellular vesicles derived from Kefir grains in a mammal in need thereof. The present invention also provides a pharmaceutical composition for ameliorating or treating IBD and/or IBS or a functional food composition for ameliorating or improving IBD and/or IBS, comprising said extracellular vesicles derived from Kefir grains as an active ingredient.

Method for ameliorating or treating a bowel disease

Disclosed is an anti-obesity active extract obtained from a medicinal plant. More specifically, the extract obtained fromfoenum-graeci herba (which is a medicinal plant traditionally used in the East) can be used as an active ingredient for a raw material, a functional food, cosmetic, a crude drug, etc. for an obesity preventing or therapeutic agent because the extract can suppress the adipocyte differentiation and decrease the body weight and body fat in an obese animal, thereby suppressing fat accumulation (that is, a factor for obesity).

Medicinal herbal extract having anti-obesity effect

Disclosed are mutated genes for green fluorescence proteins and enhanced inserted YFPs expressed therefrom. The mutant proteins not only maintain their fluorescence even at 37&#xb0; C., but also exhibit about 20 times stronger fluorescence intensities in comparison to the conventional fluorescence proteins. Accordingly, the mutant fluorescence proteins of the present invention can be used as biosensors for detecting and analyzing the bioactivities of desired materials.

Enhanced inserted yellow fluorescence protein and its application

Disclosed are the methods for producing recombinant viruses using site-specific recombination in vitro. In the present invention, circular viral genomic DNAs are digested with restriction enzymes to generate a linear form viral genomic DNAs flanked by site-specific recombination sites, and then are subjected to site-specific recombination with the desired genomic materials flanked by site-specific recombination sites in vitro. According to the present invention, since the site-specific recombination mixture can be applied to host cells without further procedures of selecting the desired recombinant viral genomic DNAs, it is possible to obtain numerous recombinant viruses rapidly at the same time. Thus, the present invention can be used as a high throughput system for generating and screening hundreds or thousands of recombinant viruses.

High throughput system for producing recombinant viruses using site-specific recombination

Growing community of inventors

Seoul, South Korea

Eun-Wook Choi