Postech Academy-industry Foundation

Seoul National University

Yonsei University

Posco

Pohang University of Science and Technology Foundation

Megagen Implant Co., Ltd.

Shin Poong Pharmaceutical Co., Ltd.

Eun Ju Oh

Sei Kwang Hahn

Sung Ho Ryu

Jung Kyu Park

Jung Hwan Lee

Kwang Bum Park

Young Soo Park

Jong In Kim

Jeong-Hoon Lee

Yoon Keun Kim

Choun-Ki Joo

Il Hwan Cho

Sung Key Jang

Jong Hun Im

Kyoung Ho Ryoo

Byung Su Kim

Jun-Sub Choi

Youndong Kim

Jong-Hoon Lim

Hyemin Kim

Hyun Wook An

Seung Kew Yoon

Seok Kyu Choi

You Me Tae

Kitae Park

Jeong-A Yang

Ki Su Kim

Jun Seok Yeom

Eui Jin Hwang

Won Jun Kang

Moo Seok Seo

Wonhee Hur

Seong Hui Jin

Seungmin Han

Jiyoun Lee

Sehoon Park

Jung Hwan Yoon

Ara Koh

Dong Jun Yang

Na-Oh Yunn

The present disclosure relates to a DNA aptamer which specifically binds to an insulin receptor, and a composition for treating diabetes and a composition for diagnosing diabetes which contain the same as an active ingredient, and the aptamer is characterized by being able to treat and diagnose diabetes more effectively than side effects caused by insulin such as increased incidence of cancer and atherosclerosis by having a different binding mechanism from existing insulin.

Aptamer against insulin receptor and pharmaceutical compostion containing the same

The present invention relates to a DNA aptamer specifically binding to a hepatocellular carcinoma-related Glypican-3 (GPC3) protein, treatment of cancers related to the Glypican-3 protein using the same, a composition for inhibiting a cancer and a composition for diagnosing a cancer comprising the same as an active ingredient.

Glypican-3 specific aptamer and use thereof

The present invention relates to a filler composition for tissue reinforcement, including hyaluronic acid and alkylene diamine crosslinked hydrogel. The filler composition exhibits the positive physical properties required for tissue reinforcement, such as biocompatibility and swelling ability, as well as useful effects in that the same can remain in vivo for a long time.

Filler composition for tissue reinforcement

The present invention relates to a drug delivery composition comprising a hyaluronic acid-peptide conjugate micelle and a production method thereof. According to the drug delivery composition and the production method of the drug-loaded, hyaluronic acid-peptide conjugate micelle of the present invention, the reaction for encapsulating can proceed in a mixed solvent of an aqueous solvent and an organic solvent. Therefore, the present invention can be applied to various types of water-insoluble active components and the biocompatible and biodegradable derivative can encapsulate a drug to provide a drug-loaded micelle, which is safe to be applied for human bodies. Moreover, the micelle has a therapeutic effect from the peptide contained therein, which can act in combination with the drug as packing therein. Therefore, the drug delivery composition and its production method can be utilized in the field of producing a sustained release formulation with an extended duration of the medicinal effect.

Drug delivery system using hyaluronic acid-peptide conjugate micelle

Provided is a bone filling complex and method of preparing the same. The bone filling complex includes a matrix including a hydrogel-type hyaluronic acid derivative; and a bone derivative filling the matrix For example, the bone filling complex can be used to regenerate an injured alveolar bone.

Bone filling complex and method for fabricating the same

Growing community of inventors

Busan, South Korea

Eun Ju Oh