Korea Institute of Science and Technology

Seoul National University

Ls Cable Ltd.

Eun-Jeong Yang

Ick Chan Kwon

Lae-Hyuk Park

Ji-Sang Park

Ju Hee Ryu

Young-Ji Ko

Ki-Yeul Kim

Nam-Hyuk Cho

Jae Won Lee

Kwan-Hee Han

Hye-Sun Kim

A probe for measuring the activity of caspase-1 according to the present disclosure can specifically image cells or tissues where inflammatory response is induced because it is cleaved by reacting specifically with the active caspase-1 enzyme in vivo and in vitro and re-emits fluorescence. The probe for measuring the activity of caspase-1 can be used for various purposes, such as for imaging of cells or tissues where inflammatory response is induced, as a drug carrier, for screening of a drug inhibiting inflammatory response, etc. The probe for measuring the activity of caspase-1 is applicable both in vivo and in vitro, and can be used for various applications such as high-throughput screening for new drug development, early diagnosis of diseases, etc.

Probe for measuring activity of Caspase-1 and composition for diagnosis of inflammatory diseases containing same

Disclosed is an optical line monitoring system and method which detects an optical line where a disorder occurs, by using an OTDR (Optical Time Domain Reflectometer) pulse pattern with matching information. The optical line monitoring system generates and stores a reference OTDR pulse pattern matched with identification information of an optical channel service unit, and compares the matched reference OTDR pulse pattern with the OTDR pulse pattern collected at an inspection time to verify an optical line region where a disorder occurs.

Optical line monitoring system and method

Growing community of inventors

Seoul, South Korea

Eun-Jeong Yang