Nextgen Bioscience Co., Ltd.

Yuha Printing & Packaging Co., Ltd.

Eun Jeong Kim

Bong Yong Lee

Yang Hae Park

Young Ah Shin

Soo Sung Kang

Mi Ji Lee

Shin Ae Kim

Ji Hun Jeong

Beak Jin Kim

Jae Hyun Choi

Na Ra Han

Su Jae Yang

Minh Thanh La

Yanghae Park

Bongyong Lee

Provided are a piperidine derivative compound, a hydrate thereof, a solvate thereof, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for the prevention or treatment of diseases related to autotaxin activity, comprising same as an active ingredient, in which the piperidine derivative compound exhibits excellent inhibitory activity against autotaxin, and thus can be effectively used in the treatment and prevention of diseases related to autotaxin inhibition, such as fibrotic diseases, inflammatory diseases, autoimmune diseases, respiratory diseases, cardiovascular diseases, metabolic diseases, cancer and cancer metastasis, ocular diseases, cholestatic form and other forms of chronic pruritus, and acute or chronic organ transplant rejection.

Piperidine derivative and pharmaceutical composition for inhibiting autotaxin comprising same

The present invention relates to a pharmaceutical composition for preventing or treating inflammatory bowel disease acting as a functional antagonist for S1PR1 and S1PR4 of S1P receptors, and more specifically, to a pharmaceutical composition including, as an active ingredient, a sphingolipid compound which does not cause cardiovascular side effects by acting as a functional antagonist for S1PR1 and S1PR4 and has an effect of preventing or treating inflammatory bowel disease.

Pharmaceutical composition for preventing or treating inflammatory bowel disease acting as a functional antagonist for S1PR1 and S1PR4

The present invention relates to a pharmaceutical composition for preventing or treating alopecia areata acting as a functional antagonist for S1P receptor's subtypes S1PR1 and S1PR4, and more particularly, relates to a pharmaceutical composition containing as an active ingredient a sphingolipid compound acting as a functional antagonist for S1PR1 and S1PR4, does not cause cardiovascular side effects, and is effective in preventing or treating alopecia areata.

Pharmaceutical composition for preventing or treating alopecia areata acting as a functional antagonist for S1PR1 and S1PR4

A packing box includes first and second sidewall parts spaced apart and facing each other, first and second connecting parts, a third connecting part attaching the second connecting part to the first sidewall part, a bottom part connecting lower portions of the first and second sidewall parts and the first and second connecting parts, and a top part facing the bottom part and connecting upper portions of the first and second sidewall parts and the first and second connecting parts to form a receiving space. The top part includes first to fourth upper paperboards folded and extended from the upper portions of the first and second sidewall parts and the first and second connecting parts to form a handle, and a fifth upper paperboard folded from the third connecting part and disposed under the first to fourth upper paperboards to prevent withdrawal of contents from the receiving space.

Packing box

Growing community of inventors

Seongnam-si, South Korea

Eun Jeong Kim