Korea Research Institute of Chemical Technology

Korea Institute of Oriental Medicine

Korea Pharma Co., Ltd.

Eun Hee Park

Jin Yeul Ma

Byung Chul Shin

Won Kyung Cho

Kwang Il Park

Seok Hee Kang

Tae Kyung Yang

Yeoun-Hee Kim

Sun Hang Cho

Tae Woo Oh

Dong-Gun Kim

The present invention relates to a pharmaceutical composition comprising a maple leaf extract or fraction thereof for preventing or treating a retinal disease, a method for preventing or treating a retinal disease using the pharmaceutical composition, and a food composition comprising a maple leaf extract or fraction thereof for ameliorating the symptoms of a retinal disease. The pharmaceutical composition according to the present invention, which is effective for the treatment of a retinal disease, can be used pharmaceutically as a composition for preventing or treating a retinal disease, and can also be used advantageously as a health functional food.

Pharmaceutical composition comprising maple leaf extract for preventing or treating retinal disease

The present invention relates to a biodegradable polymer microsphere-containing sustained-release injection containing escitalopram as an active ingredient, and to a method for manufacturing the same. In the case of escitalopram microspheres, there is a problem of low encapsulation rate, fracture due to weak strength, and initial over-release due to the phase separation of the liquid drug and the polymer inside the microspheres. In order to solve the problem, it is possible to maximize the encapsulation amount and the encapsulation efficiency of the escitalopram adding a hydrophobic solidifying agent to uniformize the non-uniform phase, to overcome the cracking of the microspheres at high loading conditions, and to properly control the initial release and release delay of the microspheres.

Microspherical sustained-release injection containing escitalopram and method for preparing same

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Seoul, South Korea

Eun Hee Park