Snur & Db Foundation

Seoul National University

Global Frontier Center for Multiscale Energy Systems

Eun Hak Lim

Jong Woo Lee

Seong Keun Kim

Jun Hee Kang

Seon Jin Hwang

Jung Eun Lee

Il Seung Yang

Il Seung Yang, Ii

Kyoung Chan Park

Seung Yang, Ii

The present application relates to a cosmetic composition comprising resveratrone, for improving skin health.

Cosmetic composition derived from natural products for improving skin health

The present invention provides a water-soluble fluorescent compound of resveratrone 6-O-&#x3b2;-glucoside [(E)-4-(8-hydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)naphthalen-2-yl)but-3-en-2-one] and its derivatives of Formula I which have at least one water-soluble substituent, and a method for preparing the same by a photochemical reaction of resveratrol 3-O-&#x3b2;-glucoside and its derivatives of having Formula 3 which are not fluorescent. Said new water-soluble fluorescent compounds has single-photon absorptive characteristics and/or two-photon absorptive characteristics as well as no or little toxicity, and can be usefully utilized in fields that requires water-soluble fluorescent characteristics (diagnosis, fluorescent probe, in vivo imaging, display, etc.).

Water-soluble fluorescence compound and method for preparing the same

The present invention provides a water-soluble fluorescent compound of resveratrone 6-O-&#x3b2;-glucoside [(E)-4-(8-hydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)naphthalen-2-yl)but-3-en-2-one] and its derivatives of Formula 1 which have at least one water-soluble substituent, and a method for preparing the same by a photochemical reaction of resveratrol 3-O-&#x3b2;-glucoside and its derivatives of having Formula 3 which are not fluorescent. Said new water-soluble fluorescent compounds has single-photon absorptive characteristics and/or two-photon absorptive characteristics as well as no or little toxicity, and can be usefully utilized in fields that requires water-soluble fluorescent characteristics (diagnosis, fluorescent probe, in vivo imaging, display, etc.).

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Seoul, South Korea

Eun Hak Lim