Quantamatrix Inc.

Eun Guen Kim

Sunghoon Kwon

Sung Hoon Kwon

Yong-Gyun Jung

Jung Il Choi

Hee Sung Kim

Jung Heon Yoo

Jungil Choi

Hyun Yong Jeong

Tae Geun Lim

Kyung-Ock Park

Sung Weon Ryoo

Haeun Kim

Hyeon Ju Jeoung

Eun Hee Lee

Hyejin Kim

Provided is a multi-well-based cell culture test device having an array structure of a plurality of aligned well units. Each of the well units includes a first sub-well adapted to accommodate a first fluid, a second sub-well adapted to accommodate a second fluid, and a barrier located between the first sub-well and the second sub-well to partition the first sub-well and the second sub-well. The first sub-well has a recess in the depth direction with respect to its bottom to accommodate a solid thin film formed by solidifying the first fluid. The barrier has such a height that the first fluid does not overflow into the second sub-well when the first fluid is loaded into the first sub-well to fill the recess.

Multi-well-based cell culture test device for rapid antibiotic susceptibility testing

The present invention relates to a novel bioactivity testing structure for single cell tracking using a gelling agent and a bioactivity testing system including the testing structure. The present invention also relates to bioactivity testing, drug susceptibility testing, antibiotic screening, and diagnostic methods using the testing structure. The bioactivity testing structure of the present invention enables very rapid and simple drug susceptibility testing of bacteria, particularly, drug screening, and bacterial diagnosis. Particularly, the use of the testing structure enables DST and diagnosis of bacteria only by pretreatment without the need to concentrate human sputum samples irrespective of inoculum effect, ensuring rapid, accurate, and simple testing compared to conventional tuberculosis diagnosis or DST systems. In addition, the testing structure of the present invention simultaneously enables the diagnosis and drug susceptibility testing of tuberculosis. Therefore, the present invention provides an effective alternative to the prior art.

Bioactivity testing structure for single cell tracking using gelling agents

Growing community of inventors

Gunpo-si, South Korea

Eun Guen Kim